Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry.
Sign Up to like & getrecommendations! Published in 2020 at "Parasitology research"
DOI: 10.1007/s00436-020-06923-w
Abstract: Lysine 2-hydroxyisobutyrylation (Khib) is a recently discovered and evolutionarily conserved form of protein post-translational modification (PTM) found in mammalian and yeast cells. Previous studies have shown that Khib plays roles in the activity of gene… read more here.
Keywords: khib; mass spectrometry; affinity; gondii ... See more keywords
Effects of lysine 2-hydroxyisobutyrylation on bacterial FabI activity and resistance to triclosan.
Sign Up to like & getrecommendations! Published in 2021 at "Biochimie"
DOI: 10.1016/j.biochi.2021.01.011
Abstract: Lysine 2-hydroxyisobutyrylation (Khib) is a novel protein posttranslational modification conserved in eukaryotes and prokaryotes. However, the biological significance of Khib remains largely unknown. Here, through screening the proteome-wide Khib modification sites in bacteria using a… read more here.
Keywords: fabi activity; khib; fabi; resistance ... See more keywords
Quantitative Proteomics Reveals the Role of Lysine 2-Hydroxyisobutyrylation Pathway Mediated by Tip60
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/4571319
Abstract: Lysine 2-hydroxyisobutyrylation (Khib) is a new type of posttranslational modifications (PTMs) extensively reported on eukaryotic cell histones. It is evolutionarily conserved and participates in diverse important biological processes, such as transcription and cell metabolism. Recently,… read more here.
Keywords: mediated tip60; khib; lysine hydroxyisobutyrylation; khib sites ... See more keywords