Dynamic monitoring of PD‐L1 and Ki67 in circulating tumor cells of metastatic non‐small cell lung cancer patients treated with pembrolizumab
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DOI: 10.1002/1878-0261.13317
Abstract: Programmed cell death protein ligand‐1 (PD‐L1) expression in non‐small cell lung cancer (NSCLC) tumors guides treatment selection. PD‐L1 expression in circulating tumor cells (CTCs) may provide further information. We have explored PD‐L1 and marker of… read more here.
Keywords: cell; non small; ki67; small cell ... See more keywords
The usefulness of CanAssist Breast over Ki67 in breast cancer recurrence risk assessment.
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DOI: 10.1002/cam4.6032
Abstract: BACKGROUND Assessment of Ki67 by immunohistochemistry (IHC) has limited utility in clinical practice owing to analytical validity issues. According to International Ki67 Working Group (IKWG) guidelines, treatment should be guided by a prognostic test in… read more here.
Keywords: ki67; canassist breast; risk; cab ... See more keywords
Assessment of Ki67 expression for breast cancer subtype classification and prognosis in the Nurses’ Health Study
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DOI: 10.1007/s10549-017-4421-3
Abstract: PurposeKi67 is a proliferation marker commonly assessed by immunohistochemistry in breast cancer, and it has been proposed as a clinical marker for subtype classification, prognosis, and prediction of therapeutic response. However, the clinical utility of… read more here.
Keywords: breast; subtype classification; breast cancer; ki67 ... See more keywords
Carcinoembryonic antigen, α-fetoprotein, and Ki67 as biomarkers and prognostic factors in intrahepatic cholangiocarcinoma: A retrospective cohort study.
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DOI: 10.1016/j.aohep.2020.07.010
Abstract: INTRODUCTION AND OBJECTIVE The purpose of this study was to investigate the expression levels and prognostic roles of α-fetoprotein (AFP), carcinoembryonic antigen (CEA), and Ki67 in tumor tissues of intrahepatic cholangiocarcinoma (ICC) patients. PATIENTS OR… read more here.
Keywords: cea; intrahepatic cholangiocarcinoma; higher afp; ki67 ... See more keywords
POWERPIINC (PreOperative Window of Endocrine TheRapy Provides Information to Increase Compliance) trial: Changes in tumor proliferation index and quality of life with 7 days of preoperative tamoxifen.
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DOI: 10.1016/j.breast.2016.11.016
Abstract: OBJECTIVES A decrease in Ki67 during neoadjuvant therapy predicts response to tamoxifen. Previous trials have shown a decreased Ki67 in breast tumors with as little as two or more weeks of preoperative tamoxifen. Shortening the… read more here.
Keywords: days preoperative; proliferation; preoperative tamoxifen; tumor proliferation ... See more keywords
Icotinib Alone or with Radio Therapy Inpatients with EGFR Mutations Non‐Small Cell Lung Cancer Who Develop Brain Metastases: P113
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.10.139
Abstract: Background: Small cell lung cancer (SCLC) has high malignancy and high metastasis rate. Ki67 as an antigen for cell proliferation, the higher the ratio, the more active the cancer cells proliferate. The aim of this… read more here.
Keywords: index; expression; ki67; cancer ... See more keywords
An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Modern Pathology"
DOI: 10.1038/s41379-018-0109-4
Abstract: The nuclear proliferation biomarker Ki67 has potential prognostic, predictive, and monitoring roles in breast cancer. Unacceptable between-laboratory variability has limited its clinical value. The International Ki67 in Breast Cancer Working Group investigated whether Ki67 immunohistochemistry… read more here.
Keywords: intraclass correlation; reproducibility; correlation coefficient; ki67 ... See more keywords
Comparison of different anti‐Ki67 antibody clones and hot‐spot sizes for assessing proliferative index and grading in pancreatic neuroendocrine tumours using manual and image analysis
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DOI: 10.1111/his.14200
Abstract: Ki67 proliferative index (PI) is essential for grading gastroenteric and pancreatic neuroendocrine tumours (GEP NETs). Analytical and preanalytical variables can affect Ki67 PI. In contrast to counting methodology, until now little attention has focused on… read more here.
Keywords: proliferative index; ki67; pancreatic neuroendocrine; using manual ... See more keywords
Expression, assessment and significance of Ki67 expression in breast cancer: an update
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DOI: 10.1136/jcp-2022-208731
Abstract: Ki67 expression is one of the most important and cost-effective surrogate markers to assess for tumour cell proliferation in breast cancer (BC). The Ki67 labelling index has prognostic and predictive value in patients with early-stage… read more here.
Keywords: ki67 expression; breast cancer; ki67; expression ... See more keywords
Abstract GS4-09: Correlative studies of the breast cancer index (HOXB13/IL17BR) and ER, PR, AR, AR/ER ratio and Ki67 for prediction of extended endocrine benefit: A trans-aTTom study
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs20-gs4-09
Abstract: Background: Several biomarkers such as estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR) and Ki67 have been implicated in the pathogenesis and/or as prognostic biomarkers of breast cancer, and are utilized to determine treatment.… read more here.
Keywords: bci; cancer; study; breast cancer ... See more keywords
The Effect of Black Cohosh on Ki67 expression and Tumor Volume: A Pilot Study of Ductal Carcinoma in Situ Patients
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DOI: 10.1177/15347354221137290
Abstract: Background: Black cohosh (BC) (Cimicifuga racemosa) may prevent and treat breast cancer through anti-proliferative, pro-apoptotic, anti-estrogenic, and anti-inflammatory effects. This study sought to evaluate the effect of BC on tumor cellular proliferation, measured by Ki67… read more here.
Keywords: ki67; tumor volume; treatment; tumor ... See more keywords