Articles with "ki67" as a keyword



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Dynamic monitoring of PD‐L1 and Ki67 in circulating tumor cells of metastatic non‐small cell lung cancer patients treated with pembrolizumab

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Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13317

Abstract: Programmed cell death protein ligand‐1 (PD‐L1) expression in non‐small cell lung cancer (NSCLC) tumors guides treatment selection. PD‐L1 expression in circulating tumor cells (CTCs) may provide further information. We have explored PD‐L1 and marker of… read more here.

Keywords: cell; non small; ki67; small cell ... See more keywords
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The usefulness of CanAssist Breast over Ki67 in breast cancer recurrence risk assessment.

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Published in 2023 at "Cancer medicine"

DOI: 10.1002/cam4.6032

Abstract: BACKGROUND Assessment of Ki67 by immunohistochemistry (IHC) has limited utility in clinical practice owing to analytical validity issues. According to International Ki67 Working Group (IKWG) guidelines, treatment should be guided by a prognostic test in… read more here.

Keywords: ki67; canassist breast; risk; cab ... See more keywords
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Assessment of Ki67 expression for breast cancer subtype classification and prognosis in the Nurses’ Health Study

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Published in 2017 at "Breast Cancer Research and Treatment"

DOI: 10.1007/s10549-017-4421-3

Abstract: PurposeKi67 is a proliferation marker commonly assessed by immunohistochemistry in breast cancer, and it has been proposed as a clinical marker for subtype classification, prognosis, and prediction of therapeutic response. However, the clinical utility of… read more here.

Keywords: breast; subtype classification; breast cancer; ki67 ... See more keywords
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Carcinoembryonic antigen, α-fetoprotein, and Ki67 as biomarkers and prognostic factors in intrahepatic cholangiocarcinoma: A retrospective cohort study.

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Published in 2020 at "Annals of hepatology"

DOI: 10.1016/j.aohep.2020.07.010

Abstract: INTRODUCTION AND OBJECTIVE The purpose of this study was to investigate the expression levels and prognostic roles of α-fetoprotein (AFP), carcinoembryonic antigen (CEA), and Ki67 in tumor tissues of intrahepatic cholangiocarcinoma (ICC) patients. PATIENTS OR… read more here.

Keywords: cea; intrahepatic cholangiocarcinoma; higher afp; ki67 ... See more keywords
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POWERPIINC (PreOperative Window of Endocrine TheRapy Provides Information to Increase Compliance) trial: Changes in tumor proliferation index and quality of life with 7 days of preoperative tamoxifen.

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Published in 2017 at "Breast"

DOI: 10.1016/j.breast.2016.11.016

Abstract: OBJECTIVES A decrease in Ki67 during neoadjuvant therapy predicts response to tamoxifen. Previous trials have shown a decreased Ki67 in breast tumors with as little as two or more weeks of preoperative tamoxifen. Shortening the… read more here.

Keywords: days preoperative; proliferation; preoperative tamoxifen; tumor proliferation ... See more keywords
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Icotinib Alone or with Radio Therapy Inpatients with EGFR Mutations Non‐Small Cell Lung Cancer Who Develop Brain Metastases: P113

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Published in 2018 at "Journal of Thoracic Oncology"

DOI: 10.1016/j.jtho.2018.10.139

Abstract: Background: Small cell lung cancer (SCLC) has high malignancy and high metastasis rate. Ki67 as an antigen for cell proliferation, the higher the ratio, the more active the cancer cells proliferate. The aim of this… read more here.

Keywords: index; expression; ki67; cancer ... See more keywords
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An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer

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Published in 2018 at "Modern Pathology"

DOI: 10.1038/s41379-018-0109-4

Abstract: The nuclear proliferation biomarker Ki67 has potential prognostic, predictive, and monitoring roles in breast cancer. Unacceptable between-laboratory variability has limited its clinical value. The International Ki67 in Breast Cancer Working Group investigated whether Ki67 immunohistochemistry… read more here.

Keywords: intraclass correlation; reproducibility; correlation coefficient; ki67 ... See more keywords
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Comparison of different anti‐Ki67 antibody clones and hot‐spot sizes for assessing proliferative index and grading in pancreatic neuroendocrine tumours using manual and image analysis

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Published in 2020 at "Histopathology"

DOI: 10.1111/his.14200

Abstract: Ki67 proliferative index (PI) is essential for grading gastroenteric and pancreatic neuroendocrine tumours (GEP NETs). Analytical and preanalytical variables can affect Ki67 PI. In contrast to counting methodology, until now little attention has focused on… read more here.

Keywords: proliferative index; ki67; pancreatic neuroendocrine; using manual ... See more keywords
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Expression, assessment and significance of Ki67 expression in breast cancer: an update

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Published in 2023 at "Journal of Clinical Pathology"

DOI: 10.1136/jcp-2022-208731

Abstract: Ki67 expression is one of the most important and cost-effective surrogate markers to assess for tumour cell proliferation in breast cancer (BC). The Ki67 labelling index has prognostic and predictive value in patients with early-stage… read more here.

Keywords: ki67 expression; breast cancer; ki67; expression ... See more keywords
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Abstract GS4-09: Correlative studies of the breast cancer index (HOXB13/IL17BR) and ER, PR, AR, AR/ER ratio and Ki67 for prediction of extended endocrine benefit: A trans-aTTom study

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Published in 2021 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs20-gs4-09

Abstract: Background: Several biomarkers such as estrogen receptor (ER), progesterone receptor (PR), androgen receptor (AR) and Ki67 have been implicated in the pathogenesis and/or as prognostic biomarkers of breast cancer, and are utilized to determine treatment.… read more here.

Keywords: bci; cancer; study; breast cancer ... See more keywords
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The Effect of Black Cohosh on Ki67 expression and Tumor Volume: A Pilot Study of Ductal Carcinoma in Situ Patients

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Published in 2022 at "Integrative Cancer Therapies"

DOI: 10.1177/15347354221137290

Abstract: Background: Black cohosh (BC) (Cimicifuga racemosa) may prevent and treat breast cancer through anti-proliferative, pro-apoptotic, anti-estrogenic, and anti-inflammatory effects. This study sought to evaluate the effect of BC on tumor cellular proliferation, measured by Ki67… read more here.

Keywords: ki67; tumor volume; treatment; tumor ... See more keywords