KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1
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DOI: 10.1038/nature21423
Abstract: The mechanistic target of rapamycin complex 1 (mTORC1) is a central regulator of cell growth that responds to diverse environmental signals and is deregulated in many human diseases, including cancer and epilepsy. Amino acids are… read more here.
Keywords: kicstor; kicstor recruits; mtorc1 signalling; rag gtpases ... See more keywords