Glomerular disease augments kidney accumulation of synthetic anionic polymers.
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DOI: 10.1016/j.biomaterials.2018.06.001
Abstract: Polymeric drug carriers can alter the pharmacokinetics of their drug cargoes, thereby improving drug therapeutic index and reducing side effects. Understanding and controlling polymer properties that drive tissue-specific accumulation is critical in engineering targeted drug… read more here.
Keywords: accumulation; anionic polymers; disease; kidney accumulation ... See more keywords