Bone morphogenetic protein‐7 incorporated polycaprolactone scaffold has a great potential to improve survival and proliferation rate of the human embryonic kidney cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28268
Abstract: Renal failures treatment has been faced with several problems during the last decades. Kidney tissue engineering has been created many hopes to improve treatment procedures with scaffold fabrication that can modulate kidney cells/stem cells migration… read more here.
Keywords: protein; kidney cells; proliferation rate; survival ... See more keywords
Protective Effect of Boric Acid Against Ochratoxin A-Induced Toxic Effects in Human Embryonal Kidney Cells (HEK293): A Study on Cytotoxic, Genotoxic, Oxidative, and Apoptotic Effects
Sign Up to like & getrecommendations! Published in 2024 at "Biological Trace Element Research"
DOI: 10.1007/s12011-024-04194-5
Abstract: The present study evaluates the protective properties of boric acid (BA) against the toxic effects induced by ochratoxin A (OTA) in human embryonic kidney cells (HEK293). The focus is on various parameters such as cytotoxicity,… read more here.
Keywords: boric acid; cells hek293; toxic effects; kidney cells ... See more keywords
Possibility of culturing the early developing kidney cells by utilizing simulated microgravity environment.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.08.012
Abstract: In recent years, the successful construction of tissues derived from established iPSCs has been disclosed, but it has been reported that the constructed tissues encounter problems of internal necrosis when their size increases. To solve… read more here.
Keywords: kidney cells; developing kidney; simulated microgravity; culture ... See more keywords
Inhibition of suppressor of cytokine signaling 1 mediates the profibrotic effect of TWEAK/Fn14 signaling on kidney cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109615
Abstract: Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) engagement with the receptor Fn14 contributes to the fibrotic process of kidney cells in systemic lupus erythematosus. Downregulation of the protein suppressor of cytokine signaling 1 (SOCS1)… read more here.
Keywords: tweak; suppressor cytokine; kidney cells; tweak fn14 ... See more keywords
Autophagy in kidney homeostasis and disease
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-020-0309-2
Abstract: Autophagy is a conserved lysosomal pathway for the degradation of cytoplasmic components. Basal autophagy in kidney cells is essential for the maintenance of kidney homeostasis, structure and function. Under stress conditions, autophagy is altered as… read more here.
Keywords: kidney cells; kidney; kidney homeostasis; disease ... See more keywords
Presence and possible impact of Fcγ receptors on resident kidney cells in health and disease
Sign Up to like & getrecommendations! Published in 2022 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12570
Abstract: Fcγ receptors (FcγRs) bind the Fc fragment of immunoglobulin G (IgG), mostly after IgG opsonizes a bacterial or viral antigen or danger/damage‐associated molecule. Consequently, classic FcγRs initiate phagocytosis of the IgG–antigen immune complex and stimulate… read more here.
Keywords: presence; kidney cells; kidney; resident kidney ... See more keywords
AK-2011 strain for the development of a vaccine against equine rhinopneumonitis.
Sign Up to like & getrecommendations! Published in 2022 at "Transboundary and emerging diseases"
DOI: 10.1111/tbed.14531
Abstract: Equine rhinopneumonitis is an acute, highly contagious disease found virtually worldwide. The purpose of the studies presented in this paper is to develop a technology for the manufacture of a cell-derived equine rhinopneumonitis vaccine, as… read more here.
Keywords: kidney cells; kidney; equine rhinopneumonitis; strain ... See more keywords
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/5696686
Abstract: Cigarette smoke (CS) is a risk factor for chronic obstructive pulmonary disease. We attempted to investigate fully the possible effects of CS on kidney cells. We found that the viability of a human kidney proximal… read more here.
Keywords: autophagy fibrosis; senescence; cigarette smoke; kidney ... See more keywords
VHL Inactivation in Precancerous Kidney Cells Induces an Inflammatory Response via ER Stress-Activated IRE1α Signaling.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-16-3196
Abstract: Mutations and epigenetic inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) are major causes of clear-cell renal cell carcinoma (ccRCC) that may originate from chronic inflammation. However, the role of VHL loss of function… read more here.
Keywords: kidney cells; response; induces inflammatory; inactivation ... See more keywords
Impact of Zinc Sulfate Exposition on Viability, Proliferation and Cell Cycle Distribution of Epithelial Kidney Cells
Sign Up to like & getrecommendations! Published in 2019 at "Polish Journal of Environmental Studies"
DOI: 10.15244/pjoes/94045
Abstract: Zinc is an essential trace element effective at very low concentrations, but it is also an important environmental pollutant dangerous after excessive intake or exposure. The aim of this study was to evaluate in vitro… read more here.
Keywords: zinc sulfate; test; cell; cell cycle ... See more keywords
Evaluation of intracellular metabolism of methotrexate in hepatocytes and embryonic kidney cells based on Folylpolyglutamate Synthetase and gamma-Glutamyl Hydrolase expression.
Sign Up to like & getrecommendations! Published in 2023 at "Current drug metabolism"
DOI: 10.2174/1389200224666230406120714
Abstract: BACKGROUND Methotrexate (MTX) is a common folic acid antagonist in clinical medicine, easily inducing a common adverse side effect of liver and kidney injury. It has been found that the expression of Folylpolyglutamate Synthetase (FPGS)… read more here.
Keywords: kidney cells; fpgs ggh; expression; fpgs ... See more keywords