Polydopamine-based quantitation of albuminuria for the assessment of kidney damage
Sign Up to like & getrecommendations! Published in 2021 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-021-03192-z
Abstract: Proteinuria is considered indicative of kidney damage that can be related to various adverse outcomes. Nowadays, there is a huge demand for routine urine screening methods to assess health risks in clinical setting without expensive… read more here.
Keywords: kidney damage; polydopamine; assessment kidney; polydopamine based ... See more keywords
Gadolinium-based contrast media exposure and the possible risk of subclinical kidney damage: a pilot study
Sign Up to like & getrecommendations! Published in 2021 at "International Urology and Nephrology"
DOI: 10.1007/s11255-020-02779-2
Abstract: We performed a pilot study to evaluate the feasibility of future research about the presence of subclinical kidney damage after Gadolinium-based contrast media exposure. The future study aims to understand which are the behaviors of… read more here.
Keywords: pilot study; kidney damage; study; damage ... See more keywords
PINK1/Parkin-mediated mitophagy is activated to protect against AFB1-induced kidney damage in mice.
Sign Up to like & getrecommendations! Published in 2022 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2022.109884
Abstract: Aflatoxin B1 (AFB1) is a toxic food pollutant that has extensive deleterious impacts on the kidney. Oxidative stress represents the primary mechanism of AFB1 nephrotoxicity and can also cause mitochondrial damage. Damaged mitochondria can trigger… read more here.
Keywords: damage; kidney damage; mediated mitophagy; parkin mediated ... See more keywords
Perfluoroalkyl substances (PFASs) exposure and kidney damage: Causal interpretation using the US 2003-2018 National Health and Nutrition Examination Survey (NHANES) datasets.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental pollution"
DOI: 10.1016/j.envpol.2021.117707
Abstract: INTRODUCTION The objective of this study was to validate the hypothesis that increased serum concentrations of perfluoroalkyl substances (PFASs) cause kidney damage. A causal interpretative study was designed using the US 2003-2018 National Health and… read more here.
Keywords: kidney damage; 2003 2018; nhanes datasets; causal ... See more keywords
Correlation between environmental low-dose cadmium exposure and early kidney damage: a comparative study in an industrial zone vs. a living quarter in Shanghai, China.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2020.103381
Abstract: To investigate heavy metal exposure in an industrial zone vs. a living quarter in Shanghai and explore the relationship between the heavy metal source and urine cadmium (Cd) and early kidney damage. Blood lead and… read more here.
Keywords: group; kidney damage; industrial zone; exposure ... See more keywords
Activation of PINK1/Parkin-mediated mitophagy protects against apoptosis in kidney damage caused by aluminum.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2022.111765
Abstract: Aluminum (Al) induces apoptosis via oxidative stress and/or mitochondrial damage. Kidney is the main organ of Al excretion, but whether Al causes apoptosis in kidney of mice remains unclear. Mitophagy maintains cell homeostasis via clearing… read more here.
Keywords: damage; kidney damage; parkin; mediated mitophagy ... See more keywords
Determination of temporal changes in serum and urinary lactate and 3-hydroxybutyrate enantiomers in mice with nephrotoxic serum nephritis by multi-dimensional HPLC.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113367
Abstract: Nephrotoxic serum (NTS) nephritis occurs in three stages: inflammation, early kidney damage, and severe kidney damage. We quantified the temporal changes in the enantiomers of lactate (LA) and 3-hydroxybutyrate (3HB) in serum and urine during… read more here.
Keywords: kidney damage; serum urinary; serum; nephrotoxic serum ... See more keywords
Methylation-dependent antioxidant-redox imbalance regulates hypertensive kidney injury in aging
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101754
Abstract: The prevalence of hypertension increases with age, and oxidative stress is a major contributing factor to the pathogenesis of hypertension-induced kidney damage in aging. The nicotinamide adenine dinucleotide phosphate (NADPH) family is one of the… read more here.
Keywords: kidney damage; methylation; redox imbalance; hypertension ... See more keywords
HIF1α blockade reduces kidney injury in lupus nephritis
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-020-0303-8
Abstract: Nature reviews | Nephrology active and pathogenic, as determined by T cell depletion experiments. Kidneyinfiltrating T cells from these mice had gene signatures suggestive of adaptations to hypoxia mediated by the transcription factor HIF1α. Chen… read more here.
Keywords: kidney damage; nephrology; hif1 blockade; lupus nephritis ... See more keywords
Synthesized gold nanoparticles mediated by Crassocephalum rubens extract down-regulate KIM-1/NGAL genes and inhibit oxidative stress in cadmium-induced kidney damage in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2022.2138427
Abstract: Cadmium (Cd) exposure induces kidney damage by mediating oxidative stress and inflammation. In this study, the role of Crassocephalum rubens-gold nanoparticles (C. rubens-AuNPs) in down-regulating kidney injury molecules-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) genes… read more here.
Keywords: kidney; ngal genes; oxidative stress; kidney damage ... See more keywords
Eucalyptol alleviates cisplatin-induced kidney damage in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2022.2156530
Abstract: This study was aimed to explore the therapeutic effect of eucalyptol on cisplatin induced kidney damage in Wistar albino rats. The animals were divided into four groups: sham (S), eucalyptol (E), cisplatin (C), and cisplatin + eucalyptol… read more here.
Keywords: induced kidney; kidney damage; group; cisplatin induced ... See more keywords