Application of Muse Cell Therapy for Kidney Diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-4-431-56847-6_11
Abstract: The kidney plays an essential role in the maintenance of homeostasis in healthy individuals, e.g., by regulating the amount of water and concentration of electrolyte in the body. Owing to the structural complexity, renal dysfunction… read more here.
Keywords: therapy; muse cell; kidney diseases; kidney ... See more keywords
Cell Apoptosis and Autophagy in Renal Fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8871-2_28
Abstract: Renal fibrosis is the final common pathway of all chronic kidney diseases progressing to end-stage renal diseases. Autophagy, a highly conserved lysosomal degradation pathway, plays important roles in maintaining cellular homeostasis in all major types… read more here.
Keywords: fibrosis; kidney diseases; cell apoptosis; renal fibrosis ... See more keywords
Epigenetic modifications of Klotho expression in kidney diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular medicine"
DOI: 10.1007/s00109-021-02044-8
Abstract: Developments of many renal diseases are substantially influenced by epigenetic modifications of numerous genes, mainly mediated by DNA methylations, histone modifications, and microRNA interference; however, not all gene modifications causally affect the disease onset or… read more here.
Keywords: modifications klotho; epigenetic modifications; kidney diseases; expression kidney ... See more keywords
Histone deacetylase 3 (HDAC3) as an important epigenetic regulator of kidney diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular medicine"
DOI: 10.1007/s00109-021-02141-8
Abstract: Development and progression of many kidney diseases are substantially influenced by aberrant protein acetylation modifications of gene expression crucial for kidney functions. Histone deacetylase (HDAC) expression alterations are detected from renal samples of patients and… read more here.
Keywords: kidney diseases; disease; histone deacetylase; hdac3 ... See more keywords
Optimizing SGLT inhibitor treatment for diabetes with chronic kidney diseases
Sign Up to like & getrecommendations! Published in 2018 at "Biological Cybernetics"
DOI: 10.1007/s00422-018-0765-y
Abstract: Diabetes induces glomerular hyperfiltration, affects kidney function, and may lead to chronic kidney diseases. A novel therapeutic treatment for diabetic patients targets the sodium–glucose cotransporter isoform 2 (SGLT2) in the kidney. SGLT2 inhibitors enhance urinary… read more here.
Keywords: chronic kidney; kidney diseases; treatment; inhibition ... See more keywords
Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities
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DOI: 10.1007/s00441-021-03499-4
Abstract: Acute and chronic kidney diseases are major contributors to morbidity and mortality in the global population. Many nephropathies are considered to be immune-mediated with dysregulated immune responses playing an important role in the pathogenesis. At… read more here.
Keywords: kidney organoid; kidney diseases; immune mediated; mediated kidney ... See more keywords
The clinical relevance of plasma CD147/basigin in biopsy-proven kidney diseases
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-017-1518-2
Abstract: BackgroundPrecise understanding of kidney disease activity is needed to design therapeutic strategies. CD147/basigin is involved in the pathogenesis of acute kidney injury and renal fibrosis through inflammatory cell infiltration. The present study examined the clinical… read more here.
Keywords: biopsy; kidney diseases; cd147; plasma cd147 ... See more keywords
The revised version 2018 of the nationwide web-based registry system for kidney diseases in Japan: Japan Renal Biopsy Registry and Japan Kidney Disease Registry
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-020-01932-6
Abstract: The Japan Renal Biopsy Registry (J-RBR), the first nation-wide registry of renal biopsies in Japan, was established in 2007, and expanded to include non-biopsy cases as the Japan Kidney Disease Registry (J-KDR) in 2009. The… read more here.
Keywords: biopsy; system; kidney diseases; japan ... See more keywords
Ferroptosis and kidney diseases
Sign Up to like & getrecommendations! Published in 2019 at "International Urology and Nephrology"
DOI: 10.1007/s11255-019-02335-7
Abstract: Ferroptosis is a form of iron-dependent, non-apoptotic regulated cell death, which is characterized by the accumulation of lipid hydroperoxides to lethal levels. Ferroptosis recently has been shown to have implications in diverse kidney diseases, such… read more here.
Keywords: nephrology; kidney diseases; ferroptosis; ferroptosis kidney ... See more keywords
Intestinal Microbiota and Kidney Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-017-2927-5
Abstract: Kidney diseases are common and the incidence rate is increasing. Gut microbiota is involved in metabolic and immune regulation of the host. Genetic, alimentary and environmental disease factors may change gut flora and increase opportunistic… read more here.
Keywords: medicine; kidney diseases; intestinal microbiota; microbiota kidney ... See more keywords
Targeting NLRP3 inflammasome as a promising approach for treatment of diabetic nephropathy: Preclinical evidences with therapeutic approaches.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173503
Abstract: Diabetes mellitus is an increasingly prevalent disease around the globe. The epidemic of diabetes mellitus and its complications pretenses the foremost health threat globally. Diabetic nephropathy is the notable complication in diabetes, leading to end-stage… read more here.
Keywords: kidney diseases; inflammasome promising; targeting nlrp3; diabetic nephropathy ... See more keywords