Different subpopulations of kidney interstitial cells produce erythropoietin and factors supporting tissue oxygenation in response to hypoxia in vivo.
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DOI: 10.1016/j.kint.2020.04.040
Abstract: Genetic induction of hypoxia signaling by deletion of the von Hippel-Lindau (Vhl) protein in mesenchymal PDGFR-β+ cells leads to abundant HIF-2 dependent erythropoietin (EPO) expression in the cortex and outer medulla of the kidney. This… read more here.
Keywords: response; response hypoxia; kidney interstitial; hypoxia ... See more keywords