Association of SGLT2 Inhibitors With Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes: A Meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2020.4511
Abstract: Importance Sodium-glucose cotransporter 2 (SGLT2) inhibitors favorably affect cardiovascular (CV) and kidney outcomes; however, the consistency of outcomes across the class remains uncertain. Objective To perform meta-analyses that assess the CV and kidney outcomes of… read more here.
Keywords: sglt2 inhibitors; death; patients type; type diabetes ... See more keywords
MO482URINE METABOLITE LEVELS OF CKD PATIENTS ARE ASSOCIATED WITH ADVERSE KIDNEY OUTCOMES AND MORTALITY*
Sign Up to like & getrecommendations! Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab087.002
Abstract: Chronic kidney disease (CKD) affects >10% of the adult population worldwide and is associated with increased risk of kidney failure (KF) and mortality. Mechanisms underlying the variable course of disease progression are incompletely understood. This… read more here.
Keywords: associated adverse; adverse kidney; metabolite levels; kidney outcomes ... See more keywords
Kidney outcomes with finerenone: an analysis from the FIGARO-DKD study
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DOI: 10.1093/ndt/gfac157
Abstract: ABSTRACT Background In FIGARO-DKD, finerenone reduced the risk of cardiovascular events in patients with type 2 diabetes (T2D) and stage 1–4 chronic kidney disease (CKD). In FIDELIO-DKD, finerenone improved kidney and cardiovascular outcomes in patients… read more here.
Keywords: figaro dkd; kidney; kidney outcomes; finerenone ... See more keywords
#1444 Albuminuria and subsequent risk of kidney events in patients with IgA nephropathy: a nationwide cohort study
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DOI: 10.1093/ndt/gfae069.406
Abstract: KDIGO recommends proteinuria 30% decline in eGFR). We also explored the risk of MAKE associated with the fold-change in uACR within a year. We enrolled 1269 patients with primary IgAN (74% men, median 53 years,… read more here.
Keywords: kidney outcomes; risk kidney; risk; uacr ... See more keywords
Albuminuria predicts kidney events in IgA nephropathy
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DOI: 10.1093/ndt/gfae085
Abstract: ABSTRACT Background and hypothesis KDIGO recommends proteinuria 30% eGFR decline. Compared with uACR < 0.3 g/g, any higher uACR category was strongly and incrementally associated with the risk of MAKE [adjusted hazard ratios (HR) ranging… read more here.
Keywords: kidney outcomes; risk; uacr; kidney ... See more keywords
#745 Sex differences across treatment response to corticosteroids and kidney outcomes in IgA nephropathy: insights from the TESTING trial
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DOI: 10.1093/ndt/gfaf116.0351
Abstract: The Therapeutic Effects of Steroids in IgA Nephropathy Global (TESTING) study found that, compared to supportive care, 6–9 months of methylprednisolone reduced the risk of major kidney events in people with IgAN at high risk… read more here.
Keywords: treatment; kidney outcomes; treatment response; risk ... See more keywords
#710 Impact of nutritional and inflammatory conditions on kidney outcomes and mortality in individuals with diabetes
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DOI: 10.1093/ndt/gfaf116.1306
Abstract: Malnutrition and chronic inflammation are not only common complications of chronic kidney disease (CKD) but also significant risk factors for the development and progression of CKD as well as mortality. Furthermore, malnutrition and inflammation are… read more here.
Keywords: kidney outcomes; tnfr2; nutritional inflammatory; individuals diabetes ... See more keywords
Evaluation of a genetic risk score based on creatinine-estimated glomerular filtration rate and its association with kidney outcomes
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DOI: 10.1093/ndt/gfx337
Abstract: Background Meta-analysis of cross-sectional genome-wide association studies (GWAS) on creatinine-estimated glomerular filtration rate (eGFRcrea) identified 53 single-nucleotide polymorphisms (SNPs). These SNP effects can be aggregated into a genetic risk score (GRS) for chronic kidney disease… read more here.
Keywords: risk; creatinine; creatinine estimated; ckd ... See more keywords
Impact of intensive blood pressure control on kidney outcomes
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DOI: 10.1097/mnh.0000000000001070
Abstract: Purpose of review Hypertension has long been recognized as a modifiable risk factor for cardiovascular events. However, the role of intensive blood pressure (BP) control in preventing kidney disease progression continues to be debated. This… read more here.
Keywords: intensive blood; kidney outcomes; control; intensive control ... See more keywords
Early reduction in albuminuria is associated with a steeper ‘dip’ in initial estimated glomerular filtration rate but favourable long‐term kidney outcomes in people with diabetes receiving sodium‐glucose cotransporter‐2 inhibitors
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DOI: 10.1111/dom.15734
Abstract: To assess if early change in albuminuria was linked to an initial change in estimated glomerular filtration rate (eGFR) and long‐term kidney outcomes in people with type 2 diabetes (T2D) receiving sodium‐glucose cotransporter‐2 (SGLT2) inhibitors. read more here.
Keywords: estimated glomerular; kidney outcomes; filtration rate; long term ... See more keywords
Body weight change associated kidney outcomes of sodium–glucose cotransporter new users
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DOI: 10.1111/dom.15808
Abstract: To investigate the clinical significance of body weight changes on kidney outcomes among individuals with diabetes using sodium–glucose cotransporter‐2 (SGLT2) inhibitors. read more here.
Keywords: kidney outcomes; glucose cotransporter; sodium glucose; body weight ... See more keywords