Predicting the risk of kidney stone formation in the nephron by ‘reverse engineering’
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DOI: 10.1007/s00240-019-01172-8
Abstract: Although most kidney stones are found in the calyx, they are usually initiated upstream in the nephron by precipitation there of certain incipient mineral phases. The risk of kidney stone formation can thus be indicated… read more here.
Keywords: stone formation; kidney stone; reverse engineering; risk kidney ... See more keywords
Stone recurrence among childhood kidney stone formers: results of a nationwide study in Iceland
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DOI: 10.1007/s00240-020-01179-6
Abstract: Objectives To examine the stone recurrence rate among childhood kidney stone formers in the Icelandic population. Materials and methods We retrospectively examined kidney stone recurrence in a recently reported population-based sample of 190 individuals who… read more here.
Keywords: stone; recurrence; stone recurrence; kidney stone ... See more keywords
Whole exome sequencing reveals heparan sulfate proteoglycan 2 (HSPG2) as a potential causative gene for kidney stone disease in a Thai family
Sign Up to like & getrecommendations! Published in 2024 at "Urolithiasis"
DOI: 10.1007/s00240-024-01674-0
Abstract: Kidney stone disease (KSD) is a prevalent and complex condition, with an incidence of 85 cases per 100,000 individuals in Thailand. Notably, over 40% of cases are concentrated in the northeastern region, indicating a potential… read more here.
Keywords: kidney stone; hspg2; family; stone disease ... See more keywords
The Emergence of Kidney Stone Disease During Childhood—Impact on Adults
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DOI: 10.1007/s11934-017-0691-x
Abstract: Purpose of ReviewThe goal of this chapter is to review the recent epidemiologic trends of kidney stone disease and discuss the impact of the increasing incidence of nephrolithiasis among children on adults with respect to… read more here.
Keywords: kidney stone; impact; disease; stone disease ... See more keywords
24-h urine test application in patients with kidney stone disease: a population-based study in a primary care setting.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of nephrology"
DOI: 10.1007/s40620-025-02389-0
Abstract: Kidney stone formation is driven by an imbalance between lithogenic substances and crystallization inhibitors. Current guidelines recommend a 24-h urine collection in patients with kidney stone disease to assess the risk of stone formation and… read more here.
Keywords: kidney stone; disease; patients kidney; stone disease ... See more keywords
Kidney Stone in a Patient with an Ileal Conduit.
Sign Up to like & getrecommendations! Published in 2017 at "European urology focus"
DOI: 10.1016/j.euf.2017.05.012
Abstract: The advantage of a retrograde over an antegrade approach in ileal conduit diversion is the lower morbidity. Furthermore, in cases in which there are bone deformities and no ureteral reflux from the reservoir into the… read more here.
Keywords: ileal conduit; patient ileal; stone patient; ileal ... See more keywords
Use of Google Trends to Track Online Behavior and Interest in Kidney Stone Surgery.
Sign Up to like & getrecommendations! Published in 2018 at "Urology"
DOI: 10.1016/j.urology.2018.05.040
Abstract: OBJECTIVE To explore internet search trends data as a unique resource for monitoring online health information-seeking behavior. We utilized Google trends to sample population interest and search inquiries into surgical treatment options of kidney stones,… read more here.
Keywords: kidney stone; search; stone; google trends ... See more keywords
Social determinants of kidney stone disease: the impact of race, income and access on urolithiasis treatment and outcomes.
Sign Up to like & getrecommendations! Published in 2021 at "Urology"
DOI: 10.1016/j.urology.2021.08.037
Abstract: The medical and surgical management of kidney stones is one of the most common functions of the urologist. Management choices are often nuanced, involving the decision to embark on one surgical plan among several options.… read more here.
Keywords: stone; stone disease; kidney stone; race ... See more keywords
Antihypertensive medications and the risk of kidney stones in older adults: a retrospective cohort study
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DOI: 10.1038/hr.2017.42
Abstract: Antihypertensives are widely prescribed and could influence kidney stone risk by altering urinary calcium excretion. However, the impact of different classes of antihypertensives on kidney stone risk is unknown. To assess this impact, we conducted… read more here.
Keywords: risk; kidney stone; risk kidney; cohort study ... See more keywords
Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis
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DOI: 10.1038/s41420-024-02117-w
Abstract: This study aims to uncover the molecular mechanisms underlying pediatric kidney stone formation induced by renal calcium deposition by utilizing high-throughput sequencing data to reveal the regulation of PINK1 by MyoD1. We performed transcriptome sequencing… read more here.
Keywords: kidney stone; pink1; oxidative stress; mitochondrial oxidative ... See more keywords
Claudin 2: role in hypercalciuria and kidney stone disease
Sign Up to like & getrecommendations! Published in 2020 at "Nature Reviews Nephrology"
DOI: 10.1038/s41581-020-0273-x
Abstract: Nature reviews | Nephrology Claudins are tight junction proteins that regulate the paracellular transport of solutes across epithelial layers. New findings demonstrate a role for the cationselective protein claudin 2 in regulating proximal tubule (Pt)… read more here.
Keywords: calcium; kidney stone; stone disease; kidney ... See more keywords