Integrated GC-MS and UHPLC-MS renal metabolomics and lipidomics deciphered the metabolic regulation mechanism of Gushudan on kidney-yang-deficiency-syndrome rats.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of separation science"
DOI: 10.1002/jssc.202300124
Abstract: Kidney-yang-deficiency-syndrome is a neuroendocrine disease caused by the dysfunction of adrenal-pituitary-target gland axis. Gushudan is a traditional Chinese medicine prescription with functions of tonifying kidney and strengthening bone, and its bone-strengthening effect has been confirmed… read more here.
Keywords: deficiency syndrome; kidney; gushudan; yang deficiency ... See more keywords
Metabolomics analysis of Semen Cuscutae protection of kidney deficient model rats using ultra high-performance liquid chromatography-quadrupole time-of-flight Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114432
Abstract: The traditional Chinese medicine syndrome "Kidney yang deficiency" is a kind of chronic kidney disease. With the development of society, the incidence of chronic kidney disease is increasing year by year, which also brings great… read more here.
Keywords: kidney yang; metabolism; analysis; deficiency ... See more keywords
1H NMR studies on serum metabonomic changes over time in a kidney-Yang deficiency syndrome model
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DOI: 10.1039/c7ra04057a
Abstract: The central aim of this study was to investigate metabolite changes in metabolic pathways via metabonomic approaches in rats suffering from Kidney-Yang Deficiency Syndrome (KYDS) induced by hydrocortisone. Metabonomic analysis using 1H NMR is a… read more here.
Keywords: kidney yang; metabolism; time; deficiency syndrome ... See more keywords
Changes in Chemical Constituents and Kidney-Yang Tonifying of Traditional Herbs After Processing: A Brief Review
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DOI: 10.1177/1934578x241250237
Abstract: Background Kidney-Yang deficiency is one of the common medical syndromes in traditional medicine, characterized by symptoms such as weakness, coldness in the lower back and knees, cold, fatigue, etc. In clinical practice, Yang tonifying medicines… read more here.
Keywords: processing; medicine; kidney yang; yang tonifying ... See more keywords
Effectiveness of Peng's Shengjing recipe on male asthenospermia caused by kidney yang deficiency: A randomized pilot study.
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DOI: 10.15537/smj.2023.44.3.20220676
Abstract: OBJECTIVES To examined the efficacy and safety of Peng's Shengjing recipe in treating asthenospermia with deficiency and failure of kidney yang. The traditional Chinese medicine (TCM) Peng's Shengjing recipe might have benefits in treating male… read more here.
Keywords: asthenospermia; shengjing recipe; peng shengjing; medicine ... See more keywords
Kidney Yang Deficiency Syndrome Exacerbates Aβ25-35-Induced Pathological Changes, And Ginsenoside Re Ameliorates Synapse Lesions In Aβ25-35-Injected Rats With Kidney Yang Deficiency Syndrome.
Sign Up to like & getrecommendations! Published in 2023 at "Current Alzheimer research"
DOI: 10.2174/1567205020666230512094230
Abstract: BACKGROUND Traditional Chinese medicine (TCM) indicates that Alzheimer's disease (AD) is considered the consequence produced by Kidney Yang Deficiency Syndrome (KDS-Yang), which has similar clinical characteristics to glucocorticoid withdrawal syndrome. Ginsenoside Re (G-Re) has been… read more here.
Keywords: deficiency syndrome; syndrome; yang deficiency; deficiency ... See more keywords
One mechanism of Sishen Pill on diarrhea with kidney Yang deficiency syndrome: influencing metabolic function by intestinal microorganisms and enzyme activity mediates the gut-kidney axis
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DOI: 10.3389/fcimb.2025.1620789
Abstract: Introduction Sishen Pill (SSP), a classic TCM formula, warms the kidney and spleen, astringes the intestine, and stops diarrhea. Emerging evidence suggests that diarrhea with KYDS is linked to gut microbiota imbalance and altered intestinal… read more here.
Keywords: count; kidney yang; enzyme activity; kidney ... See more keywords
Diarrhea with deficiency kidney-yang syndrome caused by adenine combined with Folium senna was associated with gut mucosal microbiota
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1007609
Abstract: The present study aims to study and analyze the characteristics of gut mucosal microbiota in diarrhea mice with deficiency kidney-yang syndrome. Ten male mice were randomly divided into the control group and the model group.… read more here.
Keywords: yang syndrome; kidney; deficiency kidney; mucosal microbiota ... See more keywords
Dysfunction of cecal microbiota and CutC activity in mice mediating diarrhea with kidney-yang deficiency syndrome
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DOI: 10.3389/fmicb.2024.1354823
Abstract: Objective Previous studies have indicated that diarrhea with kidney-yang deficiency syndrome leads to a disorder of small intestine contents and mucosal microbiota. However, the relationship of TMA-lyase (CutC) activity and TMAO with diarrhea with kidney-yang… read more here.
Keywords: yang deficiency; kidney yang; cutc activity; diarrhea kidney ... See more keywords
Association of intestinal mucosal barrier function with intestinal microbiota in Spleen-Kidney Yang Deficiency IBS-D mice
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DOI: 10.3389/fmicb.2025.1567971
Abstract: Background To establish and evaluate an IBS-D mouse model with Spleen-Kidney Yang Deficiency, explore the microecological mechanisms of IBS-D, and provide experimental evidence for the clinical diagnosis and treatment of IBS-D with Spleen-Kidney Yang Deficiency.… read more here.
Keywords: intestinal mucosal; yang deficiency; kidney yang; spleen kidney ... See more keywords
Characterization of the integrated gut microbiota and metabolite profiles in osteoporosis patients with different traditional Chinese medicine syndromes
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DOI: 10.3389/fmicb.2025.1663716
Abstract: Introduction This study aims to investigate whether the Traditional Chinese Medicine (TCM) classification of osteoporosis corresponds to specific gut microbial and metabolic profiles, thereby providing a microbiological basis for TCM syndrome differentiation. Methods Body composition… read more here.
Keywords: osteoporosis patients; gut microbiota; yang deficiency; medicine ... See more keywords