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   Articles with "kif11" as a keyword



KIF11, a plus end-directed kinesin, as a key gene in benzo(a)pyrene-induced non-small cell lung cancer.

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recommendations! Published in 2021 at "Environmental toxicology and pharmacology"

DOI: 10.1016/j.etap.2021.103775

Abstract: Evidence indicates that Benzo(a)pyrenediol-epoxide (BPDE) can damage lung cells, resulting in carcinogenesis with complex mechanisms. We aimed to explore the genes and pathway variations in this process. First, the key gene was screened out and… read more here.

Keywords: kif11; key gene; lung cancer; lung ... See more keywords
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KIF11 as a potential cancer prognostic marker promotes tumorigenesis in children with Wilms tumor.

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recommendations! Published in 2021 at "Pediatric hematology and oncology"

DOI: 10.1080/08880018.2021.1953655

Abstract: Emerging evidence suggests that KIF11 could play a pivotal role in cancer cell proliferation; however, its biological functions and molecular mechanisms in Wilms tumor (WT) cells are largely unknown. The aim of this study was… read more here.

Keywords: kif11; kif11 expression; expression; cancer ... See more keywords

A Novel Frameshift Variant in KIF11 Causes Autosomal Dominant Familial Exudative Vitreoretinopathy in a Chinese Family.

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recommendations! Published in 2025 at "Genetic testing and molecular biomarkers"

DOI: 10.1177/19450265251401002

Abstract: Background: Familial exudative vitreoretinopathy (FEVR) is a rare inherited ocular disorder characterized by abnormal peripheral retinal vascular development. KIF11 variants are known to cause autosomal dominant FEVR, but novel pathogenic variants remain to be identified.… read more here.

Keywords: fevr; variant; frameshift variant; chinese family ... See more keywords

Update on the Phenotypic and Genotypic Spectrum of KIF11-Related Retinopathy

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recommendations! Published in 2022 at "Genes"

DOI: 10.3390/genes13040713

Abstract: Background: This study aimed to report the frequency of KIF11-mutations in a large familial exudative vitreoretinopathy (FEVR) population, extend the clinical spectrum of KIF11-associated retinopathy and compare KIF11-associated retinopathy to FEVR with mutations in other… read more here.

Keywords: associated retinopathy; mutations genes; kif11 associated; kif11 mutations ... See more keywords