Insight into the regulation of axonal transport from the study of KIF1A-associated neurological disorder.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cell science"
DOI: 10.1242/jcs.260742
Abstract: Neuronal function depends on axonal transport by kinesin superfamily proteins (KIFs). KIF1A is the molecular motor that transports synaptic vesicle precursors, synaptic vesicles, dense core vesicles and active zone precursors. KIF1A is regulated by an… read more here.
Keywords: function; neurological disorder; axonal transport; associated neurological ... See more keywords
KIF1A-Associated Neurological Disorder: An Overview of a Rare Mutational Disease
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DOI: 10.3390/ph16020147
Abstract: KIF1A-associated neurological diseases (KANDs) are a group of inherited conditions caused by changes in the microtubule (MT) motor protein KIF1A as a result of KIF1A gene mutations. Anterograde transport of membrane organelles is facilitated by… read more here.
Keywords: neurological disorder; associated neurological; gene therapy; gene ... See more keywords