Expression and putative functions of KIFC1 for nuclear reshaping and midpiece formation during spermiogenesis of Phascolosoma esculenta.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.10.021
Abstract: Kinesin-14 KIFC1 plays an important role in vesicular transport, microtubule organization, and spermiogenesis. In this study, we first investigated the microtubule distribution and expression pattern of KIFC1 during spermiogenesis of P. esculenta. Microtubules are abundant… read more here.
Keywords: spermiogenesis; microtubule; formation; nuclear reshaping ... See more keywords
Prognostic and clinicopathological significance of kinesin family member C1 in various cancers
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017346
Abstract: Abstract Background: Kinesin family member C1 (KIFC1), a C-type kinesin motor protein, plays important roles in centrosome assembly and intracellular transport. Numerous studies have focused on the prognostic value of KIFC1 in malignant tumors and… read more here.
Keywords: family member; kinesin family; kifc1; various cancers ... See more keywords
Abstract 3965: KIFC1 is a therapeutic target in lung cancers with extra centrosomes
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3965
Abstract: Introduction: Lung cancer is a deadly malignancy and new treatments targeting mechanisms promoting its growth and progression are needed. Genomic instability (GIN) is a recurrent feature of lung tumours that promotes drug resistance and other… read more here.
Keywords: kifc1; extra centrosomes; luad; lung ... See more keywords
Abstract LB017: Potential role of kinesin family member C1 (KIFC1) in melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb017
Abstract: According to the Surveillance, Epidemiology, and End Results (SEER) analyses, based on 2017-2019 data, approximately ~2.1 percent of men and women will be diagnosed with melanoma at some point during their lifetime. Melanoma can be… read more here.
Keywords: kifc1; kinesin family; melanoma; role ... See more keywords
KIFC1 is essential for acrosome formation and nuclear shaping during spermiogenesis in the lobster Procambarus clarkii
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.16429
Abstract: In order to study the function of kinesin-14 motor protein KIFC1 during spermatogenesis of Procambarus clarkii, the full length of kifc1 was cloned from testes cDNA using Rapid-Amplification of cDNA Ends (RACE). The deduced KIFC1… read more here.
Keywords: spermiogenesis; clarkii kifc1; kifc1; procambarus clarkii ... See more keywords
Prognostic Value and Immunological Role of KIFC1 in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.799651
Abstract: As one of the members of the kinesin family, the role and potential mechanism of kinesin family member C1 (KIFC1) in the development of liver hepatocellular carcinoma (LIHC), especially in the immune infiltration, have not… read more here.
Keywords: kifc1; kifc1 mrna; hepatocellular carcinoma; role ... See more keywords
An Integrative Pan-Cancer Analysis of Kinesin Family Member C1 (KIFC1) in Human Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10030637
Abstract: Kinesin family member C1 (KIFC1) is a minus-end-directed motor protein that is critically involved in microtubule crosslinking and spindle formation. KIFC1 is essential for supernumerary centrosomes, and it is associated with the initiation and progression… read more here.
Keywords: kifc1; kinesin family; member kifc1; analysis ... See more keywords
Kinesin Motor Protein KIFC1 Is a Target Protein of miR-338-3p and Is Associated With Poor Prognosis and Progression of Renal Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology research"
DOI: 10.3727/096504018x15213115046567
Abstract: KIFC1 (kinesin family member C1) plays a critical role in clustering of extra centrosomes in various cancer cells and thus could be considered as a promising therapeutic target. However, whether KIFC1 is involved in the… read more here.
Keywords: protein; renal cell; target; mir 338 ... See more keywords
KIFC1, a novel potential prognostic factor and therapeutic target in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Oncology"
DOI: 10.3892/ijo.2018.4348
Abstract: Kinesin family member C1 (KIFC1, also known as HSET) is a minus end-directed motor protein, which is critical in centrosome clustering. The present study investigated the expression of KIFC1 in paired hepatocellular carcinoma (HCC) tissues… read more here.
Keywords: hepatocellular carcinoma; expression; potential prognostic; kifc1 ... See more keywords