Kill, but don't be killed
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.367.6473.37-e
Abstract: Cell Biology Cytotoxic T lymphocytes (CTLs) recognize and destroy infected or malignant cells. CTLs secrete the pore-forming protein perforin into the immune synapse, where perforin disrupts the target cell plasma membrane and initiates cell death… read more here.
Keywords: kill killed; target cell; perforin; biology ... See more keywords
To Kill or to Be Killed: How Does the Battle between the UPS and Autophagy Maintain the Intracellular Homeostasis in Eukaryotes?
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032221
Abstract: The ubiquitin-26S proteasome system and autophagy are two major protein degradation machineries encoded in all eukaryotic organisms. While the UPS is responsible for the turnover of short-lived and/or soluble misfolded proteins under normal growth conditions,… read more here.
Keywords: kill killed; battle ups; killed battle; protein degradation ... See more keywords