Rational Design of Evolutionarily Stable Microbial Kill Switches.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.10.002
Abstract: (Molecular Cell 68, 686–697.e1–e3; November 16, 2017) In the originally published version of this article, there was an error in Figure S3. The sequence in the figure was incorrect due to a copying error in… read more here.
Keywords: microbial kill; design evolutionarily; rational design; kill switches ... See more keywords
Genetically stable CRISPR-based kill switches for engineered microbes
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28163-5
Abstract: Microbial biocontainment is an essential goal for engineering safe, next-generation living therapeutics. However, the genetic stability of biocontainment circuits, including kill switches, is a challenge that must be addressed. Kill switches are among the most… read more here.
Keywords: crispr based; kill switch; kill; based kill ... See more keywords