A genomic‐augmented multivariate prognostic model for the survival of natural‐killer/T‐cell lymphoma patients from an international cohort
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26636
Abstract: With lowering costs of sequencing and genetic profiling techniques, genetic drivers can now be detected readily in tumors but current prognostic models for Natural‐killer/T cell lymphoma (NKTCL) have yet to fully leverage on them for… read more here.
Keywords: cell lymphoma; natural killer; killer cell;
Haploidentical hematopoietic cell transplantation as a platform for natural killer cell immunotherapy
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Hematology"
DOI: 10.1002/ajh.27471
Abstract: An innovative approach is crucially needed to manage relapse after allogeneic hematopoietic cell transplantation (HCT) in patients with advanced hematological malignancies. This review explores key aspects of haploidentical HCT with post‐transplant cyclophosphamide, highlighting the potential… read more here.
Keywords: cell transplantation; hematopoietic cell; cell; platform natural ... See more keywords
A novel prognostic model based on ferritin and nomogram‐revised risk index could better stratify patients with extranodal natural killer/T‐cell lymphoma
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DOI: 10.1002/cam4.5820
Abstract: Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is an aggressive lymphoma with marked heterogeneity, resulting in a distinct prognosis even in patients with the same disease stage. The nomogram‐revised risk index (NRI) has been proposed to… read more here.
Keywords: cell lymphoma; extranodal natural; natural killer; revised risk ... See more keywords
MOLECULAR CHARACTERIZATION OF EXTRANODAL NATURAL KILLER (NK)/T‐CELL LYMPHOMAS, NASAL TYPE FROM LATIN AMERICA
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DOI: 10.1002/hon.2437_115
Abstract: clinical trial is still ongoing (ClinicalTrials.gov, NCT 2085655). Furthermore, promising response of single agent, chidamide, a new oral HDAC inhibitor, for the treatment of relapsed or refractory NK/ TCL without significant EBV‐reactivation was recently observed… read more here.
Keywords: molecular characterization; killer cell; characterization extranodal; cell lymphomas ... See more keywords
What we should know about natural killer/T‐cell lymphomas
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DOI: 10.1002/hon.2588
Abstract: Natural‐killer/T cell lymphoma (NKTCL) is the most common extranodal lymphoma with highly aggressive clinical outcome. System biology techniques provide novel insights into the pathogenesis, risk stratification, and clinical management in NKTCL. Comparative genomic hybridization analysis… read more here.
Keywords: killer cell; know natural; cell lymphomas; natural killer ... See more keywords
Killer cell immunoglobulin‐like receptor (KIR) gene contents: Are they associated with cervical cancer?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27873
Abstract: Killer cell immunoglobulin‐like receptors (KIRs) are required for natural killer cell function against virus‐infected cells or tumor cells. KIR gene content polymorphisms in Indian women with cervical cancer (CaCx) remain unexplored. Hence, we analyzed the… read more here.
Keywords: cervical cancer; hpv infection; healthy controls; killer cell ... See more keywords
Extranodal natural killer/T cell lymphoma of the skeletal muscle
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DOI: 10.1007/s00256-024-04680-w
Abstract: This case report highlights a case of extranodal NK/T cell lymphoma initially misdiagnosed as myositis, emphasizing the appearance on both MRI and FDG PET images. The patient presented with systemic symptoms and calf muscle swelling,… read more here.
Keywords: extranodal natural; cell lymphoma; muscle; killer cell ... See more keywords
Combined gemcitabine, cisplatin, dexamethasone, methotrexate, and pegaspargase (GDP-ML) for patients with newly diagnosed extranodal natural killer/T cell lymphoma, nasal type: a single arm, single center, prospective phase 2 study
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04036-z
Abstract: Extranodal natural killer/T cell lymphoma, nasal type (ENKL) is a highly aggressive tumor with relatively poor prognosis. In this prospective study, we investigated the efficacy and toxicity of a novel GDP-ML regimen (combined gemcitabine, cisplatin,… read more here.
Keywords: killer cell; newly diagnosed; natural killer; extranodal natural ... See more keywords
Exploring natural killer cell-related biomarkers in multiple myeloma: a novel nature killer cell-related model predicting prognosis and immunotherapy response using single-cell study
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DOI: 10.1007/s10238-024-01322-2
Abstract: Background Natural killer cells (NKs) may be involved in multiple myeloma (MM) progression. The present study elucidated the correlation between NKs and the progression of MM using single-cell binding transcriptome probes to identify NK cell-related… read more here.
Keywords: analysis; cell; model; killer cell ... See more keywords
A Batf3/Nlrp3/IL-18 Axis Promotes Natural Killer Cell IL-10 Production during Listeria monocytogenes Infection
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DOI: 10.1016/j.celrep.2018.04.106
Abstract: SUMMARY The bacterial pathogen Listeria monocytogenes (Lm) capitalizes on natural killer (NK) cell production of regulatory interleukin (IL)-10 to establish severe systemic infections. Here, we identify regulators of this IL-10 secretion. We show that IL-18… read more here.
Keywords: killer cell; production; natural killer; infection ... See more keywords
Natural killer cell responses to emerging viruses of zoonotic origin
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DOI: 10.1016/j.coviro.2020.07.003
Abstract: Emerging viral diseases pose a major threat to public health worldwide. Nearly all emerging viruses, including Ebola, Dengue, Nipah, West Nile, Zika, and coronaviruses (including SARS-Cov2, the causative agent of the current COVID-19 pandemic), have… read more here.
Keywords: cell responses; killer cell; emerging viruses; natural killer ... See more keywords