KIN17 promotes cell migration and invasion through stimulating the TGF‐β/Smad2 pathway in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23492
Abstract: KIN17 DNA and RNA binding protein (Kin17) is involved in the regulation of tumorigenesis of diverse human cancers. However, its role in the cancer progression and metastasis in hepatocellular carcinoma (HCC) remains largely unknown. Bioinformatics… read more here.
Keywords: smad2 pathway; migration invasion; kin17; tgf smad2 ... See more keywords
Kin17 facilitates thyroid cancer cell proliferation, migration, and invasion by activating p38 MAPK signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-020-03939-9
Abstract: Kin17 DNA and RNA binding protein (Kin17) is an extremely conserved nuclear protein that is almost expressed in every type of mammal cells. Recently, Kin17 has been implicated into the regulation of tumorigenesis of diverse… read more here.
Keywords: cell proliferation; kin17; signaling pathway; cell ... See more keywords
Knockdown of DNA/RNA-binding protein KIN17 promotes apoptosis of triple-negative breast cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Letters"
DOI: 10.3892/ol.2018.9597
Abstract: Effective therapy for breast cancer has been extensively studied worldwide, particularly for triple-negative breast cancer and drug-resistant subtypes. DNA/RNA-binding protein KIN17 (kin17) has been reported to be significantly upregulated in breast cancer cells, and is… read more here.
Keywords: breast; apoptosis; kin17; breast cancer ... See more keywords
Roles and regulatory mechanisms of KIN17 in cancers (Review)
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Letters"
DOI: 10.3892/ol.2023.13723
Abstract: KIN17, which is known as a DNA and RNA binding protein, is highly expressed in numerous types of human cancers and was discovered to participate in several vital cell behaviors, including DNA replication, damage repair,… read more here.
Keywords: cell; regulatory mechanisms; roles regulatory; mechanisms kin17 ... See more keywords