Characterization of the preferred cation cofactors of chloroplast protein kinases in Arabidopsis thaliana
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13563
Abstract: Chloroplasts sense a variety of stimuli triggering several acclimation responses. One prominent response is the mechanism of state transitions, which enables rapid adaption to changes in illumination. Here, we investigated the link between divalent cations… read more here.
Keywords: kinase activity; characterization preferred; chloroplast protein;
Ataxia‐telangiectasia: A review of movement disorders, clinical features and genotype correlations ‐ Addendum
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.27449
Abstract: Since the online publication of our article, two relevant reports have been published that merit mention. In one, a 27 year old woman with a past history of recurrent infections and elevated AFP level developed… read more here.
Keywords: kinase activity; movement; clinical features; ataxia telangiectasia ... See more keywords
Quantitative and Dynamic Imaging of ATM Kinase Activity.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6940-1_9
Abstract: Ataxia telangiectasia mutated (ATM) is a serine/threonine kinase critical to the cellular DNA-damage response, including DNA double-strand breaks (DSBs). ATM activation results in the initiation of a complex cascade of events facilitating DNA damage repair,… read more here.
Keywords: dna damage; kinase activity; kinase; atm kinase ... See more keywords
Quantification of Cell Signaling Networks Using Kinase Activity Chemosensors.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7154-1_4
Abstract: The ability to directly determine endogenous kinase activity in tissue homogenates provides valuable insights into signaling aberrations that underlie disease phenotypes. When activity data is collected across a panel of kinases, a unique "signaling fingerprint"… read more here.
Keywords: kinase activity; kinase; cell signaling; signaling networks ... See more keywords
Measurements of Photoreaction and Kinase Activity of Phototropin, a Photoreceptor Protein for Tropic Response in Plants: Involvement of Kinase Activity in the Photosensitivity of Tropic Response.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9015-3_14
Abstract: Phototropin is a photoreceptor protein responsible for phototropic responses in plants. A phototropin molecule has two photoreceptive domains named LOV1 and LOV2 in the N-terminal region. Blue light absorbed by a chromophore in these domains… read more here.
Keywords: phototropin; kinase; kinase activity; tropic response ... See more keywords
Kinase activity-dependent stability of calcium/calmodulin-dependent protein kinase of Lotus japonicus
Sign Up to like & getrecommendations! Published in 2019 at "Planta"
DOI: 10.1007/s00425-019-03264-6
Abstract: Main conclusionAccumulation of calcium/calmodulin-dependent protein kinase (CCaMK) in root cell nucleus depends on its kinase activity but not on nuclear symbiotic components crucial for nodulation.AbstractPlant calcium/calmodulin-dependent protein kinase (CCaMK) is a key regulator of symbioses… read more here.
Keywords: protein; kinase activity; kinase; calcium ... See more keywords
UMP kinase activity is involved in proper chloroplast development in rice
Sign Up to like & getrecommendations! Published in 2017 at "Photosynthesis Research"
DOI: 10.1007/s11120-017-0477-5
Abstract: Isolation of leaf-color mutants is important in understanding the mechanisms of chloroplast biogenesis and development. In this study, we identified and characterized a rice (Oryza sativa) mutant, yellow leaf 2 (yl2), exhibiting pale yellow leaves… read more here.
Keywords: ump kinase; chloroplast development; kinase activity; development ... See more keywords
Insights into ligand stimulation effects on gastro-intestinal stromal tumors signalling.
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DOI: 10.1016/j.cellsig.2016.10.009
Abstract: Mutations in KIT or PDGFRA are responsible for >85% of gastrointestinal stromal tumors. The introduction of imatinib in the GIST therapy scheme revolutionized the patient outcome. Unfortunately, the therapy allows the disease stabilization instead of… read more here.
Keywords: kinase activity; stromal tumors; gist; kit mutants ... See more keywords
Homeodomain Proteins Directly Regulate ATM Kinase Activity
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DOI: 10.1016/j.celrep.2018.06.089
Abstract: SUMMARY Ataxia-telangiectasia mutated (ATM) is a serine/threonine kinase that coordinates the response to DNA double-strand breaks and oxidative stress. NKX3.1, a prostate-specific transcription factor, was recently shown to directly stimulate ATM kinase activity through its… read more here.
Keywords: kinase activity; kinase; homeodomain proteins; atm kinase ... See more keywords
Saccharomyces cerevisiae polo-like kinase, Cdc5 exhibits ATP-dependent Mg2+-enhanced kinase activity in vitro
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DOI: 10.1016/j.heliyon.2019.e03050
Abstract: Phosphorylation of proteins on serine/threonine residues represents an important biochemical mechanism to regulate several cellular processes. Polo-like kinases (PLKs) are a family of serine-threonine kinases that play an imminent role in cell cycle regulation in… read more here.
Keywords: cdc5; kinase; kinase activity; gst cdc5 ... See more keywords
The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice
Sign Up to like & getrecommendations! Published in 2020 at "Neuron"
DOI: 10.1016/j.neuron.2020.03.005
Abstract: DNA sequence variants in the TBK1 gene associate with or cause sporadic or familial amyotrophic lateral sclerosis (ALS). Here we show that mice bearing human ALS-associated TBK1 missense loss-of-function mutations, or mice in which the… read more here.
Keywords: kinase activity; loss tbk1; motor neurons; tbk1 kinase ... See more keywords