A-Kinase-Anchoring Protein (AKAP150) is expressed in Astrocytes and Upregulated in Response to Ischemia
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.05.019
Abstract: A-kinase-anchoring proteins, AKAPs, are scaffolding proteins that associate with kinases and phosphatases, and direct them to a specific submembrane site to coordinate signaling events. AKAP150, a rodent ortholog of human AKAP79, has been extensively studied… read more here.
Keywords: akap150; anchoring protein; protein akap150; ischemia ... See more keywords
A-Kinase Anchoring Protein 150 (AKAP150) Promotes Cocaine Reinstatement by Increasing AMPA Receptor Transmission in the Accumbens Shell
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychopharmacology"
DOI: 10.1038/npp.2017.297
Abstract: Previous work indicated that activation of D1-like dopamine receptors (D1DRs) in the nucleus accumbens shell promoted cocaine seeking through a process involving the activation of PKA and GluA1-containing AMPA receptors (AMPARs). A-kinase anchoring proteins (AKAPs)… read more here.
Keywords: cocaine reinstatement; accumbens shell; reinstatement; transmission ... See more keywords
A-Kinase Anchoring Protein 9 Promotes Gastric Cancer Progression as a Downstream Effector of Cadherin 1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2830634
Abstract: Background Genetic studies identified a dozen of frequently mutated genes in gastric cancer, such as cadherin 1 (CDH1) and A-kinase anchoring protein 9 (AKAP9). Of note, genetic alterations including depletion and amplification frameshift mutations of… read more here.
Keywords: kinase anchoring; cadherin; gastric cancer; anchoring protein ... See more keywords
Serum level of A-kinase anchoring protein 1, negatively correlated with insulin resistance and body mass index, decreases slightly in people with newly diagnosed T2DM.
Sign Up to like & getrecommendations! Published in 2020 at "Endokrynologia Polska"
DOI: 10.5603/ep.a2020.0051
Abstract: BACKGROUND to investigate relationship between serum levels of A-kinase anchoring protein 1 (AKAP1) and T2DM. MATERIAL AND METHODS 261 subjects were involved in the experiment, including 130 patients with newly diagnosed T2DM and 131 people… read more here.
Keywords: serum; kinase anchoring; t2dm; anchoring protein ... See more keywords