Part III: Novel checkpoint kinase 2 (Chk2) inhibitors; design, synthesis and biological evaluation of pyrimidine-benzimidazole conjugates.
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DOI: 10.1016/j.ejmech.2018.01.072
Abstract: Recently a dramatic development of the cancer drug discovery has been shown in the field of targeted cancer therapy. Checkpoint kinase 2 (Chk2) inhibitors offer a promising approach to enhance the effectiveness of cancer chemotherapy.… read more here.
Keywords: checkpoint kinase; chk2; kinase chk2; chk2 inhibitors ... See more keywords