Redefining the Protein Kinase Conformational Space with Machine Learning.
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DOI: 10.1016/j.chembiol.2018.05.002
Abstract: Protein kinases are dynamic, adopting different conformational states that are critical for their catalytic activity. We assess a range of structural features derived from the conserved αC helix and DFG motif to define the conformational… read more here.
Keywords: kinase conformational; kinase; conformation; protein kinase ... See more keywords