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Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19974-5
Abstract: Inositol-Requiring Enzyme 1 (IRE1) is an essential component of the Unfolded Protein Response. IRE1 spans the endoplasmic reticulum membrane, comprising a sensory lumenal domain, and tandem kinase and endoribonuclease (RNase) cytoplasmic domains. Excess unfolded proteins…
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Keywords:
kinase front;
kinase;
atp competitive;
rnase ... See more keywords