Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity.
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DOI: 10.1021/acs.jmedchem.8b00613
Abstract: There is an urgent need for strategies to combat dengue and other emerging viral infections. We reported that cyclin G-associated kinase (GAK), a cellular regulator of the clathrin-associated host adaptor proteins AP-1 and AP-2, regulates… read more here.
Keywords: associated kinase; gak; kinase gak; cyclin associated ... See more keywords