Hydrogen Sulfide-linked Persulfidation of ABSCISIC INSENSITIVE 4 Controls Arabidopsis ABA Responses Through the Transactivation of Mitogen-Activated Protein Kinase Kinase Kinase 18.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular plant"
DOI: 10.1016/j.molp.2021.03.007
Abstract: Hydrogen sulfide (H2S) is a signaling molecule that regulates plant hormone and stress responses. The phytohormone abscisic acid (ABA) plays important role during plant adaptation to unfavorable environmental conditions and induces the persulfidation of L-CYSTEINE… read more here.
Keywords: plant; persulfidation; kinase; abi4 ... See more keywords
Mitogen-Activated Protein Kinase Kinase 5 Regulates Proliferation and Biosynthetic Processes in Procyclic Forms of Trypanosoma brucei.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.7b00415
Abstract: The pathogenic protozoan T. brucei alternates into distinct developmental stages in the mammalian and insect hosts. The mitogen-activated protein kinase (MAPK) signaling pathways transduce extracellular stimuli into a range of cellular responses, which ultimately lead… read more here.
Keywords: kinase; activated protein; protein kinase; kinase kinase ... See more keywords
Selective protection of human cardiomyocytes from anthracycline cardiotoxicity by small molecule inhibitors of MAP4K4
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68907-1
Abstract: Given the poor track record to date of animal models for creating cardioprotective drugs, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have been proposed as a therapeutically relevant human platform to guide target validation and cardiac… read more here.
Keywords: protection; inhibitors map4k4; cell death; kinase kinase ... See more keywords
Hsa_circ_0000877 facilitates the progression of diffuse large B-cell lymphoma by miR-370-3p/mitogen-activated protein kinase kinase kinase kinase 4/Hippo pathway
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001366
Abstract: Diffuse large B-cell lymphoma (DLBCL) originates from B lymphocytes and is a fatal hematological malignancy. Circular RNAs have been increasingly reported as a promising biological target for cancer therapy, but their role in DLBCL remains… read more here.
Keywords: mir 370; cell; circ 0000877; kinase kinase ... See more keywords
Regulation of secretory pathway kinase or kinase-like proteins in human cancers
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DOI: 10.3389/fimmu.2023.942849
Abstract: Secretory pathway kinase or kinase-like proteins (SPKKPs) are effective in the lumen of the endoplasmic reticulum (ER), Golgi apparatus (GA), and extracellular space. These proteins are involved in secretory signaling pathways and are distinctive from… read more here.
Keywords: like proteins; pathway kinase; kinase like; kinase ... See more keywords
Molecular Insights of MAP4K4 Signaling in Inflammatory and Malignant Diseases
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DOI: 10.3390/cancers15082272
Abstract: Simple Summary The mitogen-activated protein kinase (MAPK) pathway plays a crucial role in inflammatory and malignant diseases. The MAPK signaling cascade is mediated by various members of the MAP4K, MAP3K, MAP2K, and MAPK families. One… read more here.
Keywords: role; kinase; inflammatory; map4k4 ... See more keywords
miR-490-5p regulates the proliferation, migration, invasion and epithelial-mesenchymal transition of pharyngolaryngeal cancer cells by targeting mitogen-activated protein kinase kinase kinase 9
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2022.5129
Abstract: Following the publication of the above article, an interested reader drew to the authors' attention that the 'Control' and 'NC' data panels for the invasion assay experiments with the FaDu cell line in Fig. 5D on… read more here.
Keywords: medicine; kinase; molecular medicine; kinase kinase ... See more keywords