Identification of novel MEK1 inhibitors by pharmacophore and docking based virtual screening
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DOI: 10.1007/s00044-017-1788-y
Abstract: AbstractMitogen-activated protein kinase/mitogen-activated protein kinase kinase1 plays a key role in the Ras/Raf/MEK/ERK signaling pathway associated with cell growth, differentiation and development. In an effort to identify novel mitogen-activated protein kinase kinase1 inhibitors, an efficient… read more here.
Keywords: virtual screening; activated protein; kinase kinase1; protein kinase ... See more keywords