Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family.
Sign Up to like & getrecommendations! Published in 2018 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2017.11.001
Abstract: Human COQ8A (ADCK3) and Saccharomyces cerevisiae Coq8p (collectively COQ8) are UbiB family proteins essential for mitochondrial coenzyme Q (CoQ) biosynthesis. However, the biochemical activity of COQ8 and its direct role in CoQ production remain unclear,… read more here.
Keywords: small molecule; coq8; kinase like; family ... See more keywords
Ceramide kinase‐like protein promotes cutaneous squamous cell carcinoma
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DOI: 10.1111/bjd.20442
Abstract: Linked Article: Meyer et al. Br J Dermatol 2021; 185:147–152 . read more here.
Keywords: kinase like; like protein; ceramide kinase; promotes cutaneous ... See more keywords
Cyclin-Dependent Kinase-Like 5 (CDKL5): Possible Cellular Signalling Targets and Involvement in CDKL5 Deficiency Disorder
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DOI: 10.1155/2020/6970190
Abstract: Cyclin-dependent kinase-like 5 (CDKL5, also known as STK9) is a serine/threonine protein kinase originally identified in 1998 during a transcriptional mapping project of the human X chromosome. Thereafter, a mutation in CDKL5 was reported in… read more here.
Keywords: cyclin dependent; disorder; kinase like; dependent kinase ... See more keywords
Regulation of secretory pathway kinase or kinase-like proteins in human cancers
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DOI: 10.3389/fimmu.2023.942849
Abstract: Secretory pathway kinase or kinase-like proteins (SPKKPs) are effective in the lumen of the endoplasmic reticulum (ER), Golgi apparatus (GA), and extracellular space. These proteins are involved in secretory signaling pathways and are distinctive from… read more here.
Keywords: like proteins; pathway kinase; kinase like; kinase ... See more keywords