Diacylglycerol kinase ΞΆ limits IL-2-dependent control of PD-1 expression in tumor-infiltrating T lymphocytes
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DOI: 10.1136/jitc-2020-001521
Abstract: Background The inhibitory functions triggered by the programmed cell death-1 (PD-1) receptor following binding to its ligand (PD-L1) protect healthy organs from cytotoxic T cells, and neutralize antitumor T cell attack. Antibody-based therapies to block… read more here.
Keywords: kinase limits; expression; control expression; diacylglycerol kinase ... See more keywords