Inhibition of RhoA and mTORC2/Rictor by Fingolimod (FTY720) induces p21-activated kinase 1, PAK-1 and amplifies podosomes in mouse peritoneal macrophages.
Sign Up to like & getrecommendations! Published in 2018 at "Immunobiology"
DOI: 10.1016/j.imbio.2018.07.009
Abstract: Macrophage functions in the immune response depend on their ability to infiltrate tissues and organs. The penetration between and within the tissues requires degradation of extracellular matrix (ECM), a function performed by the specialized, endopeptidase-… read more here.
Keywords: p21 activated; activated kinase; podosomes mouse; kinase pak ... See more keywords