Molecular and clinicopathologic characterization of pediatric histiocytoses.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of hematology"
DOI: 10.1002/ajh.26938
Abstract: The spectrum of somatic mutations in pediatric histiocytoses and their clinical implications are not fully characterized, especially for non-Langerhans cell histiocytosis (-LCH) subtypes. A cohort of 415 children with histiocytosis from the French histiocytosis registry… read more here.
Keywords: histiocytosis; molecular clinicopathologic; map kinase; pediatric histiocytoses ... See more keywords
Statins ameliorate pulmonary hypertension secondary to left ventricular dysfunction through the Rho‐kinase pathway and NADPH oxidase
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23610
Abstract: Pulmonary hypertension (PH) is a devastating disorder, for which no therapy is curative. It has been reported that pulmonary vascular remodeling, associated with increasing mean pulmonary arterial pressure and upregulated expression of endothelial nitric oxide… read more here.
Keywords: pulmonary hypertension; kinase pathway; secondary left; ventricular dysfunction ... See more keywords
MAP kinase signaling pathway in pulmonary adenocarcinomas: A study from India: 62P
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/s1556-0864(18)30338-1
Abstract: Background: Tyrosine kinase inhibitors (TKIs) are effective in EGFR and ALK driven non-small cell lung cancer (NSCLC). However, drug insensitivity, tumor recurrence, and resistance caused by second mutations in the EGFR or aberrant bypass signaling… read more here.
Keywords: kinase pathway; kinase; study; pulmonary adenocarcinomas ... See more keywords
Plant chemical genetics reveals colistin sulphate as a SA and NPR1-independent PR1 inducer functioning via a p38-like kinase pathway
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-47526-5
Abstract: In plants, low-dose of exogenous bacterial cyclic lipopeptides (CLPs) trigger transient membrane changes leading to activation of early and late defence responses. Here, a forward chemical genetics approach identifies colistin sulphate (CS) CLP as a… read more here.
Keywords: kinase pathway; like kinase; genetics; kinase ... See more keywords
Network modeling and analysis of MAP Kinase pathway to assess role of genes in tumor development.
Sign Up to like & getrecommendations! Published in 2025 at "Physical biology"
DOI: 10.1088/1478-3975/ae25af
Abstract: Despite decades of research, cancer remains one of the biggest health challenges. Due to the intricate interplay between multiple factors and different cancer types, it is still impossible to pinpoint a common cause for all… read more here.
Keywords: cancer; role; kinase pathway; tumor ... See more keywords
JTE‐013 supplementation improves erectile dysfunction in rats with streptozotocin‐induced type Ⅰ diabetes through the inhibition of the rho‐kinase pathway, fibrosis, and apoptosis
Sign Up to like & getrecommendations! Published in 2019 at "Andrology"
DOI: 10.1111/andr.12716
Abstract: Erectile dysfunction (ED) is a common complication in patients with diabetes mellitus (DM) that severely affects the patients' quality of life. However, the effectiveness of oral phosphodiesterase type 5 inhibitors in these patients is poor.… read more here.
Keywords: jte 013; kinase pathway; erectile dysfunction; type ... See more keywords
The Conserved CNOT1 Interaction Motif of Tristetraprolin Regulates ARE-mRNA Decay Independently of the p38 MAPK-MK2 Kinase Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and Cellular Biology"
DOI: 10.1128/mcb.00055-22
Abstract: The regulation of the mRNA decay activator Tristetraprolin (TTP) by the p38 mitogen-activated protein kinase (MAPK) pathway during the mammalian inflammatory response represents a paradigm for the control of mRNA turnover by signaling. TTP activity… read more here.
Keywords: tristetraprolin; p38 mapk; mrna decay; ttp ... See more keywords
The TOR kinase pathway is relevant for nitrogen signaling and antagonism of the mycoparasite Trichoderma atroviride
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262180
Abstract: Trichoderma atroviride (Ascomycota, Sordariomycetes) is a well-known mycoparasite applied for protecting plants against fungal pathogens. Its mycoparasitic activity involves processes shared with plant and human pathogenic fungi such as the production of cell wall degrading… read more here.
Keywords: tor; kinase pathway; trichoderma atroviride; nitrogen ... See more keywords
Effect of alpha-linolenic acid on aminoglycoside nephrotoxicity and RhoA/Rho-kinase pathway in kidney
Sign Up to like & getrecommendations! Published in 2024 at "PeerJ"
DOI: 10.7717/peerj.18335
Abstract: Aminoglycoside nephrotoxicity stands as a primary contributor to the development of acute intrinsic renal failure. Distinctive characteristic associated with this nephrotoxicity is the occurrence of tubular necrosis, which is why it is commonly referred to… read more here.
Keywords: gentamicin; kinase pathway; rho; rho kinase ... See more keywords