Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence
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DOI: 10.1242/jcs.213587
Abstract: ABSTRACT Lysosomes receive and degrade cargo from endocytosis, phagocytosis and autophagy. They also play an important role in sensing and instructing cells on their metabolic state. The lipid kinase PIKfyve generates phosphatidylinositol-3,5-bisphosphate to modulate lysosome… read more here.
Keywords: pikfyve; lysosome enlargement; pikfyve inhibition; inhibition ... See more keywords