Docking Approach to Predict Inhibition Activity of New Pt(II) Complexes Against Kinase Protein and Human DNA: Full Characterization, HF-FC Modeling and Genotoxicity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Inorganic and Organometallic Polymers and Materials"
DOI: 10.1007/s10904-019-01233-w
Abstract: New series of Pt(II)–azaindazole complexes, were synthesized and also characterized by, analytical, spectral and computational tools. All synthesized Pt(II)-complexes, appeared as mononuclear with bi-dentate mode of bonding. Octahedral arrangement as well as square-planer, were proposed… read more here.
Keywords: kinase protein; docking approach; dna; inhibition ... See more keywords
Fibroblast growth factor 5 overexpression ameliorated lipopolysaccharide-induced apoptosis of hepatocytes through regulation of the phosphoinositide-3-kinase/protein kinase B pathway
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002540
Abstract: Abstract Background: Sepsis is a systemic inflammatory syndrome induced by several infectious agents. Multiple organs are affected by sepsis, including the liver, which plays an important role in metabolism and immune homeostasis. Fibroblast growth factors… read more here.
Keywords: sepsis; protein kinase; apoptosis; kinase protein ... See more keywords