Identification of a RON tyrosine kinase receptor binding peptide using phage display technique and computational modeling of its binding mode
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-017-3437-2
Abstract: RON (Recepteur d’Origine Nantais) tyrosine kinase receptor is a promising target for therapeutic intervention in cancer therapy. The aim of this work was identification of RON-binding peptides using phage display and computational modeling their mode… read more here.
Keywords: phage; ron; using phage; identification ron ... See more keywords
Mechanisms of PAR-1 mediated kinase receptor transactivation: Smad linker region phosphorylation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-019-00527-5
Abstract: Protease activated receptors (PARs) transactivate both epidermal growth factor receptors (EGFR) and transforming growth factor (TGF)-β receptors (TGFBR1) in vascular smooth muscle leading to the increased expression of genes (CHST11 and CHSY1) which are rate… read more here.
Keywords: phosphorylation; transactivation; linker region; smad linker ... See more keywords
Corrigendum to “Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications”
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DOI: 10.1155/2018/3714684
Abstract: [This corrects the article DOI: 10.1155/2016/9214056.]. read more here.
Keywords: corrigendum tyrosine; landscape lung; lung cancer; kinase receptor ... See more keywords
Serine-Threonine Kinase Receptor Associate Protein (STRAP) Confers Stemness in Neuroblastoma
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DOI: 10.1542/peds.147.3_meetingabstract.919-a
Abstract: Background: Serine-threonine kinase receptor associated protein (STRAP) is a scaffolding protein that has been implicated in tumor growth and metastasis. The role of STRAP in neuroblastoma (NB) has not been explored. Stem cell-like cancer cells… read more here.
Keywords: threonine kinase; strap; kinase receptor; protein strap ... See more keywords