Phospho‐inositide‐dependent kinase 1 regulates signal dependent translation in megakaryocytes and platelets
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14748
Abstract: Regulated protein synthesis is essential for megakaryocyte (MK) and platelet functions, including platelet production and activation. PDK1 (phosphoinositide‐dependent kinase 1) regulates platelet functional responses and has been associated with circulating platelet counts. Whether PDK1 also… read more here.
Keywords: phospho inositide; dependent kinase; inositide dependent; regulates signal ... See more keywords
NF-κB Inducing Kinase Regulates Intestinal Immunity and Homeostasis
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DOI: 10.3389/fimmu.2022.895636
Abstract: Intestinal immunity and homeostasis are maintained through the regulation of cytokine trafficking, microbiota, necrosis and apoptosis. Intestinal immunity and homeostasis participate in host defenses and inflammatory responses locally or systemically through the gut-organ axis. NF-κB… read more here.
Keywords: inducing kinase; intestinal immunity; kinase regulates; immunity homeostasis ... See more keywords
Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function
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DOI: 10.3390/ijms24108806
Abstract: Ribosomal S6 Kinases (S6Ks) are critical regulators of cell growth, homeostasis, and survival, with dysregulation of these kinases being associated with various malignancies. While S6K1 has been extensively studied, S6K2 has been neglected despite its… read more here.
Keywords: ribosomal kinase; function; kinase regulates; survival ... See more keywords