Articles with "kinase regulates" as a keyword



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Phospho‐inositide‐dependent kinase 1 regulates signal dependent translation in megakaryocytes and platelets

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Published in 2020 at "Journal of Thrombosis and Haemostasis"

DOI: 10.1111/jth.14748

Abstract: Regulated protein synthesis is essential for megakaryocyte (MK) and platelet functions, including platelet production and activation. PDK1 (phosphoinositide‐dependent kinase 1) regulates platelet functional responses and has been associated with circulating platelet counts. Whether PDK1 also… read more here.

Keywords: phospho inositide; dependent kinase; inositide dependent; regulates signal ... See more keywords

Abstract 6939: MAPKAP kinase 2 regulates inflammatory responses in glioblastoma

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-6939

Abstract: IDH-wildtype glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor in adults, with 5-year survival rates of only 6% and a median survival of 14-22 months, depending on the MGMT promoter methylation… read more here.

Keywords: kinase regulates; mk2; gbm; tumor ... See more keywords

NF-κB Inducing Kinase Regulates Intestinal Immunity and Homeostasis

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.895636

Abstract: Intestinal immunity and homeostasis are maintained through the regulation of cytokine trafficking, microbiota, necrosis and apoptosis. Intestinal immunity and homeostasis participate in host defenses and inflammatory responses locally or systemically through the gut-organ axis. NF-κB… read more here.

Keywords: inducing kinase; intestinal immunity; kinase regulates; immunity homeostasis ... See more keywords

Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24108806

Abstract: Ribosomal S6 Kinases (S6Ks) are critical regulators of cell growth, homeostasis, and survival, with dysregulation of these kinases being associated with various malignancies. While S6K1 has been extensively studied, S6K2 has been neglected despite its… read more here.

Keywords: ribosomal kinase; function; kinase regulates; survival ... See more keywords