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Upstream regulators of phosphoinositide 3‐kinase and their role in diseases

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.28215

Abstract: Phosphoinositide 3‐kinase (PI3K), a crucial signaling molecule, is regulated by various upstream regulators. Traditionally, receptor tyrosine kinases and G protein‐coupled receptor are regarded as its principle upstream regulators; however, recent reports have indicated that spleen… read more here.

Keywords: kinase role; regulators phosphoinositide; upstream regulators; role diseases ... See more keywords