Tyrosine Kinase 2 and Janus Kinase‒Signal Transducer and Activator of Transcription Signaling and Inhibition in Plaque Psoriasis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2021.06.869
Abstract: Plaque psoriasis is a common, chronic, systemic, immune-mediated inflammatory disease. The Janus kinase‒signal transducer and activator of transcription (JAK-STAT) pathway plays a major role in intracellular cytokine signaling in inflammatory processes involved in psoriasis. Although… read more here.
Keywords: jak; plaque psoriasis; signal transducer; kinase signal ... See more keywords
Janus kinase-signal transducers and activators of transcription cell signaling in Spondyloarthritis: rationale and evidence for JAK inhibition.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in rheumatology"
DOI: 10.1097/bor.0000000000000810
Abstract: PURPOSE OF REVIEW The Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling proteins represent a group of intracellular kinase molecules that play a central role in the signaling pathways induced by cytokines, chemokines, and… read more here.
Keywords: signal transducers; activators transcription; janus kinase; kinase signal ... See more keywords