TANK-binding kinase 1 (TBK1): an emerging therapeutic target for drug discovery.
Sign Up to like & getrecommendations! Published in 2021 at "Drug discovery today"
DOI: 10.1016/j.drudis.2021.05.016
Abstract: Dysregulation of TANK-binding kinase 1 (TBK1) homeostasis leads to the occurrence and progression of many diseases, such as inflammation, autoimmune diseases, metabolic diseases, and cancer. Therefore, there is a need to develop TBK1 inhibitors as… read more here.
Keywords: drug discovery; tank binding; binding kinase; kinase tbk1 ... See more keywords
Targeting TANK-binding kinase 1 (TBK1) in cancer
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2020.1826929
Abstract: ABSTRACT Introduction TANK-binding kinase 1 (TBK1) is a Ser/Thr kinase with a central role in coordinating the cellular response to invading pathogens and regulating key inflammatory signaling cascades. While intact TBK1 signaling is required for… read more here.
Keywords: tank binding; kinase tbk1; tbk1 cancer; tbk1 ... See more keywords