Abstract 5336: Discovery of a novel activin receptor-like kinases (ALKs) inhibitor targeting TGF-β signaling pathways
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DOI: 10.1158/1538-7445.am2023-5336
Abstract: Introduction: Transforming growth factor β (TGF-β) plays a key role in promoting tumor progression mainly through facilitating angiogenesis, epithelial-mesenchymal transition (EMT) and also inducing immunosuppression in tumor microenvironment, allowing cancer cells to escape immune surveillance.… read more here.
Keywords: kinases alks; receptor like; activin receptor; like kinases ... See more keywords