Proteome-Wide Characterizations of N6-Methyl-Adenosine Triphosphate- and N6-Furfuryl-Adenosine Triphosphate-Binding Capabilities of Kinases.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c02565
Abstract: Kinases catalyze the transfer of the γ-phosphate group from adenosine triphosphate (ATP) to their protein and small-molecule substrates, and this phosphorylation is a crucial element of multiple cell signaling pathways. Herein, we employed isotope-coded ATP… read more here.
Keywords: atp; adenosine triphosphate; endogenous kinases; proteome wide ... See more keywords
Ndr/Lats kinases bind specific Mob-family coactivators through a conserved and modular interface.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b01096
Abstract: Ndr/Lats kinases bind Mob coactivator proteins to form complexes that are essential and deeply conserved components of "Hippo" signaling pathways, which control cell proliferation and morphogenesis in eukaryotes. All Ndr/Lats kinases have a characteristic N-terminal… read more here.
Keywords: ndr lats; specific mob; lats kinases; interface ... See more keywords