Human Kinases Display Mutational Hotspots at Cognate Positions Within Cancer
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DOI: 10.1142/9789813207813_0039
Abstract: The discovery of driver genes is a major pursuit of cancer genomics, usually based on observing the same mutation in different patients. But the heterogeneity of cancer pathways plus the high background mutational frequency of… read more here.
Keywords: kinases display; kinase paralogs; display mutational; human kinases ... See more keywords