Design, Synthesis and Characterization of 2-pyridone Derivatives as C-Jun N-terminal Kinases (JNKs) Signaling Pathway Inhibitors
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DOI: 10.5958/0974-360x.2017.00684.9
Abstract: A new series of 2-pyridone derivatives (A1-A6) were synthesized by various substitution and their structures were confirmed by spectral and elemental analyses. The cytotoxic activities of the newly synthesized compounds were docked against JNKs (2WAJ… read more here.
Keywords: pyridone derivatives; jun terminal; kinases jnks; terminal kinases ... See more keywords