High-throughput profiling of sequence recognition by tyrosine kinases and SH2 domains using bacterial peptide display
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DOI: 10.7554/elife.82345
Abstract: Tyrosine kinases and SH2 (phosphotyrosine recognition) domains have binding specificities that depend on the amino acid sequence surrounding the target (phospho)tyrosine residue. Although the preferred recognition motifs of many kinases and SH2 domains are known,… read more here.
Keywords: recognition; tyrosine; sh2 domains; tyrosine kinases ... See more keywords