Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia.
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DOI: 10.1021/acs.jmedchem.1c00804
Abstract: Serine/threonine-protein kinases 3 and 4 (STK3 and STK4, respectively) are key components of the Hippo signaling pathway, which regulates cell proliferation and death and provides a potential therapeutic target for acute myeloid leukemia (AML). Herein,… read more here.
Keywords: kinases stk3; stk3 stk4; myeloid leukemia; stk4 ... See more keywords