Dietary flavonoids-rich Citrus reticulata peel extract interacts with CREB signaling to suppress seizures and linked neurobehavioral impairments in a kindling mouse model
Sign Up to like & getrecommendations! Published in 2022 at "Nutritional Neuroscience"
DOI: 10.1080/1028415x.2022.2071807
Abstract: ABSTRACT Objectives: The citrus fruits peel contains a variety of bioactive metabolites that have shown multiple therapeutic effects. However, despite having substantial ethnomedicinal value, citrus peels remained underexplored and regarded as bio-waste. This present study… read more here.
Keywords: citrus reticulata; kindled animals; peel extract; creb signaling ... See more keywords
Deep brain stimulation restores the glutamatergic and GABAergic synaptic transmission and plasticity to normal levels in kindled rats
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0224834
Abstract: Background The precise effect of low frequency stimulation (LFS) as a newly postulated, anticonvulsant therapeutic approach on seizure-induced changes in synaptic transmission has not been completely determined. Hypothesis In this study, the LFS effect on… read more here.
Keywords: synaptic transmission; kindled animals; gene expression; kindled rats ... See more keywords