The Role of the Possible Receptors and Intracellular Pathways in Protective Effect of Exogenous Anandamide in Kindling Model of Epilepsy.
Sign Up to like & getrecommendations! Published in 2022 at "Neurochemical research"
DOI: 10.1007/s11064-021-03517-5
Abstract: In this research, the involvement of CB1 and TRPV1 receptors in the possible protective effects of anandamide were investigated in the kindling model of epilepsy. The basolateral amygdala of the rat brain was chosen to… read more here.
Keywords: model epilepsy; group; effect; kindling model ... See more keywords
Unraveling the Effects of GSK-3β Isoform Modulation against Limbic Seizures and in the 6 Hz Electrical Kindling Model for Epileptogenesis.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00782
Abstract: Two closely related glycogen synthase kinase-3 (GSK-3) isoforms have been identified in mammals: GSK-3α and GSK-3β. GSK-3β is the most prominent in the central nervous system and was previously shown to control neuronal excitability. We… read more here.
Keywords: gsk gsk; kindling model; model; mice ... See more keywords
Differential Effects of a Full and Biased Ghrelin Receptor Agonist in a Mouse Kindling Model
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DOI: 10.3390/ijms20102480
Abstract: The ghrelin system has received substantial recognition as a potential target for novel anti-seizure drugs. Ghrelin receptor (ghrelin-R) signaling is complex, involving Gαq/11, Gαi/o, Gα12/13, and β-arrestin pathways. In this study, we aimed to deepen… read more here.
Keywords: ghrelin receptor; receptor agonist; agonist; receptor ... See more keywords