Kinesin family member 18B: A contributor and facilitator in the proliferation and metastasis of cutaneous melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22409
Abstract: Melanoma is the most aggressive type of cutaneous tumor and the occurrence of metastasis makes it resistant to almost all available treatment and becomes incorrigible. Hence, identifying metastasis‐related biomarkers and effective therapeutic targets will assist… read more here.
Keywords: melanoma; family member; proliferation; metastasis ... See more keywords
Kinesin family member 2A links with advanced tumor stage, reduced chemosensitivity and worse prognosis in gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24313
Abstract: Kinesin family member 2A (KIF2A) induces gastric cancer (GC) growth and invasion, while its clinical relevance in GC patients is not reported. This study aimed to investigate the linkage of KIF2A with clinicopathological features, prognosis,… read more here.
Keywords: family member; kinesin family; gastric cancer;
Kinesins in MAPK cascade: How kinesin motors are involved in the MAPK pathway?
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2018.10.042
Abstract: Kinesins are essential for the transport and positioning of several biomolecules through moving along the microtubule in eukaryotic cells. Up to now, there are 14 kinesin family proteins known. The MAPK pathway which is composed… read more here.
Keywords: kinesin kinesin; mapk cascade; mapk pathway; kinesin ... See more keywords
miR-139-3p/Kinesin family member 18B axis suppresses malignant progression of gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2033466
Abstract: ABSTRACT miR-139-3p exerts tumor-suppressing functions in various cancers. We analyzed and identified that miR-139-3p expression was notably low in gastric cancer (GC) via edgeR differential analysis based on The Cancer Genome Atlas database and quantitative… read more here.
Keywords: cancer; family member; kinesin family; gastric cancer ... See more keywords
Prognostic and clinicopathological significance of kinesin family member C1 in various cancers
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017346
Abstract: Abstract Background: Kinesin family member C1 (KIFC1), a C-type kinesin motor protein, plays important roles in centrosome assembly and intracellular transport. Numerous studies have focused on the prognostic value of KIFC1 in malignant tumors and… read more here.
Keywords: family member; kinesin family; kifc1; various cancers ... See more keywords
High kinesin family member 18A expression correlates with poor prognosis in primary lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.13051
Abstract: Lung adenocarcinoma (LUAD) is the most prevalent pathological subtype of lung cancer. Kinesin family member 18A (KIF18A) plays an important role in tumorigenesis. Its roles in breast cancer, colorectal cancer, and other tumors have been… read more here.
Keywords: lung adenocarcinoma; member 18a; family member; cancer ... See more keywords
High kinesin family member 11 expression predicts poor prognosis in patients with clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2018-205390
Abstract: Aims Kinesin family member 11 (Kif11) is a member of the kinesin family motor proteins, which is associated with spindle formation and tumour genesis. In this study, we investigated the relationship between Kif11 expression and… read more here.
Keywords: cell; expression; kif11 expression; kinesin family ... See more keywords
Abstract LB017: Potential role of kinesin family member C1 (KIFC1) in melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb017
Abstract: According to the Surveillance, Epidemiology, and End Results (SEER) analyses, based on 2017-2019 data, approximately ~2.1 percent of men and women will be diagnosed with melanoma at some point during their lifetime. Melanoma can be… read more here.
Keywords: kifc1; kinesin family; melanoma; role ... See more keywords
Kinesin Family Member C1 Increases Temozolomide Resistance of Glioblastoma Through Promoting DNA Damage Repair
Sign Up to like & getrecommendations! Published in 2021 at "Cell Transplantation"
DOI: 10.1177/0963689721991466
Abstract: Glioblastoma (GBM) is one of the most frequent primary malignant brain tumors with a poor prognosis. Unfortunately, due to the intrinsic or acquired chemoresistance of GBM cells, it easily becomes refractory disease and tumors are… read more here.
Keywords: dna damage; family member; glioblastoma; gbm ... See more keywords
Single-motor and multi-motor motility properties of kinesin-6 family members
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DOI: 10.1242/bio.059533
Abstract: ABSTRACT Kinesin motor proteins are responsible for orchestrating a variety of microtubule-based processes including intracellular transport, cell division, cytoskeletal organization, and cilium function. Members of the kinesin-6 family play critical roles in anaphase and cytokinesis… read more here.
Keywords: kinesin family; multi motor; motility; transport ... See more keywords
Kinesin-14 family proteins and microtubule dynamics define S. pombe mitotic and meiotic spindle assembly, and elongation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.240234
Abstract: ABSTRACT To segregate the chromosomes faithfully during cell division, cells assemble a spindle that captures the kinetochores and pulls them towards opposite poles. Proper spindle function requires correct interplay between microtubule motors and non-motor proteins.… read more here.
Keywords: spindle assembly; mitotic meiotic; family; microtubule dynamics ... See more keywords