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Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16328-z
Abstract: Within the mitotic spindle, kinesin motors cross-link and slide overlapping microtubules. Some of these motors exhibit off-axis power strokes, but their impact on motility and force generation in microtubule overlaps has not been investigated. Here,…
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Keywords:
kinesin motors;
antiparallel microtubules;
microtubules around;
right handed ... See more keywords
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1
Published in 2019 at "Soft matter"
DOI: 10.1039/c8sm01877d
Abstract: We study the dynamics of a tunable 2D active nematic liquid crystal composed of microtubules and kinesin motors confined to an oil-water interface. Kinesin motors continuously inject mechanical energy into the system through ATP hydrolysis,…
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Keywords:
active nematics;
kinesin motors;
autonomous flows;
properties autonomous ... See more keywords
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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2108046119
Abstract: Significance Kinesin-14 motors represent an essential class of molecular motors that bind to microtubules and then walk toward the microtubule minus-end. However, whether these motors can interact with growing plus-ends of microtubules to impact the…
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Keywords:
kinesin motors;
plus ends;
microtubule plus;
microtubule ... See more keywords
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2
Published in 2023 at "Journal of Cell Science"
DOI: 10.1242/jcs.260735
Abstract: ABSTRACT Microtubules are critical for a variety of important functions in eukaryotic cells. During intracellular trafficking, molecular motor proteins of the kinesin superfamily drive the transport of cellular cargoes by stepping processively along the microtubule…
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Keywords:
microtubule lattice;
kinesin motors;
microtubule;
kinesin ... See more keywords
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1
Published in 2022 at "eLife"
DOI: 10.7554/elife.82228
Abstract: Bidirectional cargo transport in neurons requires competing activity of motors from the kinesin-1, -2 and -3 superfamilies against cytoplasmic dynein-1. Previous studies demonstrated that when kinesin-1 attached to dynein-dynactin-BicD2 (DDB) complex, the tethered motors move…
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Keywords:
bidirectional transport;
cargo transport;
kinesin motors;
transport ... See more keywords