Trypanosomes have divergent kinesin-2 proteins that function differentially in flagellum biosynthesis and cell viability.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cell science"
DOI: 10.1242/jcs.129213
Abstract: Trypanosoma brucei, the causative agent of African sleeping sickness, has a flagellum that is crucial for motility, pathogenicity, and viability. In most eukaryotes, the intraflagellar transport (IFT) machinery drives flagellum biogenesis, and anterograde IFT requires… read more here.
Keywords: biosynthesis; viability; cell; kinesin proteins ... See more keywords
Emerging Insights into the Function of Kinesin-8 Proteins in Microtubule Length Regulation
Sign Up to like & getrecommendations! Published in 2018 at "Biomolecules"
DOI: 10.3390/biom9010001
Abstract: Proper regulation of microtubules (MTs) is critical for the execution of diverse cellular processes, including mitotic spindle assembly and chromosome segregation. There are a multitude of cellular factors that regulate the dynamicity of MTs and… read more here.
Keywords: emerging insights; kinesin; function kinesin; kinesin proteins ... See more keywords