Advances in Stereoconvergent Catalysis from 2005 to 2015: Transition-Metal-Mediated Stereoablative Reactions, Dynamic Kinetic Resolutions, and Dynamic Kinetic Asymmetric Transformations.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.6b00731
Abstract: Stereoconvergent catalysis is an important subset of asymmetric synthesis that encompasses stereoablative transformations, dynamic kinetic resolutions, and dynamic kinetic asymmetric transformations. Initially, only enzymes were known to catalyze dynamic kinetic processes, but recently various synthetic… read more here.
Keywords: asymmetric transformations; resolutions dynamic; stereoconvergent catalysis; kinetic asymmetric ... See more keywords
Pd-Catalyzed Dynamic Kinetic Asymmetric Cross-Coupling of Heterobiaryl Bromides with N-Tosylhydrazones
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DOI: 10.1021/acs.orglett.2c01355
Abstract: A dynamic kinetic asymmetric Pd-catalyzed cross-coupling reaction of heterobiaryl bromides with ketone N-tosylhydrazones for the synthesis of heterobiaryl styrenes is described. The combination of Pd(dba)2 as a precatalyst with a TADDOL-derived phosphoramidite ligand provides the… read more here.
Keywords: dynamic kinetic; heterobiaryl bromides; kinetic asymmetric; cross coupling ... See more keywords
Energetics of Dynamic Kinetic Asymmetric Transformation in Suzuki–Miyaura Coupling
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DOI: 10.1021/acscatal.9b05526
Abstract: The enantioselective cross-coupling reactions that transform a racemic mixture into an enantio-enriched product are in high contemporary demand. Elucidation of mechanism involving catalytic enantio... read more here.
Keywords: asymmetric transformation; kinetic asymmetric; dynamic kinetic; transformation suzuki ... See more keywords
Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c02150
Abstract: A stereodivergent Pd/Cu catalyst system has been developed for the unprecedented dynamic kinetic asymmetric transformation (DyKAT) of racemic unsymmetrical 1,3-disubstituted allylic acetates with prochiral aldimine esters. A series of α,α-disubstituted α-amino acids bearing vicinal stereocenters… read more here.
Keywords: unsymmetrical disubstituted; racemic unsymmetrical; asymmetric transformation; kinetic asymmetric ... See more keywords