Kinetic Characterization of Prenyl-Flavin Synthase from Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry"
DOI: 10.1021/acs.biochem.7b01131
Abstract: We have characterized the kinetics and substrate requirements of prenyl-flavin synthase from yeast. This enzyme catalyzes the addition of an isopentenyl unit to reduced flavin mononucleotide (FMN) to form an additional six-membered ring that bridges… read more here.
Keywords: kinetic characterization; characterization prenyl; prenyl flavin; flavin synthase ... See more keywords
Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.2c00165
Abstract: SARS-CoV-2 non-structural protein 13 (nsp13) is a highly conserved helicase and RNA 5′-triphosphatase. It uses the energy derived from the hydrolysis of nucleoside triphosphates for directional movement along the nucleic acids and promotes the unwinding… read more here.
Keywords: kinetic characterization; small molecule; sars cov; atpase activity ... See more keywords
Regenerable Biosensors for Small-Molecule Kinetic Characterization Using SPR
Sign Up to like & getrecommendations! Published in 2020 at "SLAS Discovery"
DOI: 10.1177/2472555220975358
Abstract: A key activity in small-molecule drug discovery is the characterization of compound–target interactions. Surface plasmon resonance (SPR) is a flexible technique for this purpose, with a wide affinity range (micromoles to picomoles), low protein requirements,… read more here.
Keywords: immobilization; regenerable biosensors; kinetic characterization; small molecule ... See more keywords
Kinetic characterization of acetone monooxygenase from Gordonia sp. strain TY-5
Sign Up to like & getrecommendations! Published in 2018 at "AMB Express"
DOI: 10.1186/s13568-018-0709-x
Abstract: Acetone monooxygenase (ACMO) is a unique member of the Baeyer–Villiger monooxygenase (BVMO) family based on its ability to act on small ketones, such as acetone. Herein, we performed a kinetic analysis of ACMO from the… read more here.
Keywords: acetone monooxygenase; kinetic characterization; monooxygenase; gordonia strain ... See more keywords
Preliminary Kinetic Characterization of Lithium–Aluminum Based Hydrides for Airbreathing Propulsion
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Propulsion and Power"
DOI: 10.2514/1.b36307
Abstract: The aim of this research is to present a preliminary experimental investigation on the behavior of lithium–aluminum complex hydrides when exposed to gaseous nitrogen in the range of 20–350°C for ai... read more here.
Keywords: propulsion; kinetic characterization; lithium; lithium aluminum ... See more keywords